Improvement of bone fracture characteristics based on microstructural considerations
| Project/Area Number |
24500503
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Hirosaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YOKOTA Hideo 理化学研究所, 画像情報処理研究チーム, チームリーダー (00261206)
TODOH Masahiro 北海道大学, 大学院工学研究院, 准教授 (10314402)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 生物・生体工学 / 機械材料・材料力学 / 生体材料 / 物性実験 / 医療・福祉 / 骨折予防 |
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| Outline of Final Research Achievements |
Bone tissue is a composite material consisting of hydroxyapatite-like mineral particles and collagen fibers. The stiffness of the tissue is strongly dependent on the form of apatite phase. Mechanical properties of cortical bone vary drastically with the change of apatite concentration under demineralization processes. Thus we focused on the demineralization to improve the fracture toughness of bone tissue. In this study, we developed a Charpy-type impact loading device for bone fracture tests. And we showed that the demineralization process increased the impact toughness of bovine cortical bone specimens. And the demineralization improved the impact toughness of notched specimens even if the process was locally applied to the defected area.
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Report
(4 results)
Research Products
(14 results)
