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Development of nocturnal home hemodialysis system with navigator

Research Project

Project/Area Number 24500517
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionTokyo Women's Medical University

Principal Investigator

MINESHIMA MICHIO  東京女子医科大学, 医学部, 教授 (50166097)

Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords生物・生体工学 / 医用・福祉 / 化学工学 / 臨床工学 / 在宅透析 / モニタリング / 透析装置 / モニタリングシステム / 透析液排液 / LED / アルゴリズム / 吸光度 / レーザー血流計
Outline of Final Research Achievements

IThe aim of this study is development of nocturnal home hemodialysis system with a navigator in safety. Concretely, continuous monitoring systems for solute removal characteristics and patient’s peripheral blood flow during the treatment have been developed to navigate the optimal dialysis conditions for each patient. Time course of absorbance at 280 nm strongly correlated with UN concentration profile during the treatment. A real-time monitor for albumin leakage could be developed by using detective techniques for albumin concentration in the spent dialysate based on the difference of the absorbance values between the pre- and post- filtration for the spent dialysate.
During our study, we have reached some conclusions. Development of fundamental techniques and collecting some knowledge are done for the nocturnal dialysis system with navigator at home. Development of a dialysis machine with the navigation system is required for optimum dialysis for each patient in the near future.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (15 results)

All 2016 2015 2014 2013 2012 Other

All Journal Article (3 results) Presentation (9 results) (of which Invited: 5 results) Book (3 results)

  • [Journal Article] 適正透析実現に向けたナビゲーション透析システムの開発2014

    • Author(s)
      山本 健一郎, 峰島 三千男
    • Journal Title

      日本透析医会雑誌

      Volume: 29 Pages: 144-146

    • Related Report
      2014 Research-status Report
  • [Journal Article] Development of intermittent infusion hemodiafiltration using ultra pure dialysis fluid with an automated dialysis machine2013

    • Author(s)
      Mineshima, M, Eguchi K
    • Journal Title

      Blood Purification

      Volume: 35 Issue: Suppl. 1 Pages: 55-58

    • DOI

      10.1159/000346371

    • Related Report
      2013 Research-status Report
  • [Journal Article] 血液透析器の溶質除去特性「内部濾過現象を意識した新しい設計概念」2012

    • Author(s)
      峰島三千男
    • Journal Title

      膜

      Volume: 37 Pages: 28-34

    • NAID

      10030450092

    • Related Report
      2012 Research-status Report
  • [Presentation] UV排液モニタで算出される透析量と各溶質の除去率、除去量との比較検討2016

    • Author(s)
      平川 晋也、石森 勇、峰島 三千男、他
    • Organizer
      第44回東京透析懇談会
    • Place of Presentation
      東京
    • Year and Date
      2016-02-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] 日機装社製透析量モニタ(DDM)による透析液排液中のアルブミン濃度測定の基礎的検討2015

    • Author(s)
      若山 功治、平川 晋也、峰島 三千男、ほか
    • Organizer
      第21回日本HDF研究会
    • Place of Presentation
      熊本市
    • Year and Date
      2015-09-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 透析領域におけるモニタリング技術の進歩:レーザー血流計を中心に2015

    • Author(s)
      峰島 三千男
    • Organizer
      第19回日本アクセス研究会学術集会・総会
    • Place of Presentation
      広島市
    • Year and Date
      2015-09-12
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 透析領域におけるモニタリングの有用性と進歩2015

    • Author(s)
      峰島 三千男
    • Organizer
      第24回日本次世代人工腎臓研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-09-05
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 透析液排液中溶質の濃度モニタリング2015

    • Author(s)
      山本 健一郎 、江口 圭、峰島 三千男、他
    • Organizer
      第60回日本透析医学会総会・学術集会
    • Place of Presentation
      横浜市
    • Year and Date
      2015-06-26
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 透析液排液中溶質濃度連続モニタリングの可能性2015

    • Author(s)
      山本 健一郎, 江口 圭, 平川 晋也, 村上 淳, 秋葉 隆, 峰島 三千男
    • Organizer
      日本医工学治療学会第31回学術大会
    • Place of Presentation
      広島市
    • Year and Date
      2015-03-28 – 2015-03-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 透析液排液中溶質濃度の連続モニタリング2014

    • Author(s)
      山本 健一郎, 峰島 三千男
    • Organizer
      第59回日本透析医学会学術集会・総会
    • Place of Presentation
      神戸市
    • Year and Date
      2014-06-13 – 2014-06-15
    • Related Report
      2014 Research-status Report
  • [Presentation] 透析中の各種モニタリングの有用性2013

    • Author(s)
      峰島 三千男
    • Organizer
      第8回クリアランスギャップ研究会学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 透析療法におけるモニタリング技術を極める

    • Author(s)
      峰島三千男
    • Organizer
      第5回血液浄化工学セミナー
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
    • Invited
  • [Book] 最新透析医療 先端技術の融合2016

    • Author(s)
      平川 晋也、石森 勇、峰島 三千男、他
    • Total Pages
      859
    • Publisher
      医薬ジャーナル社
    • Related Report
      2015 Annual Research Report
  • [Book] 最新透析医療 先端技術の融合2016

    • Author(s)
      山本 健一郎 、江口 圭、峰島 三千男、他
    • Total Pages
      859
    • Publisher
      医薬ジャーナル社
    • Related Report
      2015 Annual Research Report
  • [Book] 全人力・科学力・透析力・for the people 透析医学2014

    • Author(s)
      山本 健一郎, 峰島 三千男
    • Total Pages
      720
    • Publisher
      医薬ジャーナル社
    • Related Report
      2014 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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