A study on the evaluation of instantaneous heart rate estimation accuracy

• Project/Area Number: 24500518
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Biomedical engineering/Biological material science
• Research Institution: Hosei University
• Principal Investigator: YANA Kazuo 法政大学, 理工学部, 教授 (50138244)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000); Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 生体信号処理 / 心拍変動 / 自律神経 / 周波数解析 / 無侵襲計測 / スプライン関数 / 瞬時心拍数 / 心拍ゆらぎ / 無侵襲測定 / IPFMモデル / 周波数測定 / 1/f雑音 / DCSI法 / 心拍変動解析 / スペクトル解析 / 心臓突然死 / 心電図 / データ平滑化 / スプラン関数

Outline of Final Research Achievements

Heart rate is fluctuating due to the autonomic nervous activity. Spectral analysis of the heart rate variability has been known to be effective for noninvasive evaluation of the autonomic nervous activity. There are several methods to reconstruct the instantaneous heart rate signals from RR intervals, but researchers are selecting the method heuristically. This research intend to introduce indices to evaluate the accuracy of instantaneous heart rate reconstruction method. A new index named effective bandwidth has been shown to be effective for the evaluation. DCSI has been identified as the best heart rate reconstruction method but accompany the estimation bias at the high frequency region. The research found a blending method of DCSI and SIHR yielded a better estimation accuracy without any bias in estimated spectral pattern. The proposed method will be useful not only to evaluate the accuracy of the heart rate reconstruction accuracy but also useful to create new algorithm

Research Products

• [Journal Article] Long and Short Term QT-RR Interval Co-Variability in Type 2 Diabetes (2014)
  • Author(s): Masaki Furuya, YutaMasuda, Kei Sato, Toshihiro Nishibe, Kazuo Yana, and Takuya Ono
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc. Volume: 1 Pages: 38-41
  • DOI: 10.1109/embc.2014.6943523
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A new Index for Evaluating Instantaneous Heart Rate Reconstruction Accuracy (2014)
  • Author(s): Ichiro Joja, Naoto Higuchi, Hidenao Nagai, Mitsuki Aihara, Kazuo Yana
  • Journal Title: International Journal of Bioelectromagnetism Volume: 16 Pages: 32-35
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Greater insulin resistance indicates decreased diurnal variation in the QT interval in patients with type 2 diabetes (2014)
  • Author(s): Kotoko Tanaka, Kenji Yodogawa,Takuya Ono, Kazuo Yana, Masaaki, Miyamoto, Hirotsugu Atarashi, Takao Kato & Kyoichi Mizuno
  • Journal Title: Heart and Vessels Volume: 29 Issue: 2 Pages: 256-262
  • DOI: 10.1007/s00380-013-0356-8
  • Peer Reviewed
• [Journal Article] T-wave Alternans Search over 24 Hour Holter ECG Recordings based on Singular Value Decomposition (2013)
  • Author(s): Toshihiro Nishibe, Koichiro Yamashiro, Kazuo Yana and Takuya Ono
  • Journal Title: Proc. 35th Annual International Conference of the IEEE EMBS Volume: Proceedings Pages: 2076-2079
  • DOI: 10.1109/embc.2013.6609941
  • Peer Reviewed
• [Journal Article] Autonomic State Classification based on Incremental Heart Rate Spectra (2013)
  • Author(s): Shunya Kaneko, Yutaka Yasumoto, Kazuo Yana, and Takuya Ono
  • Journal Title: International J. Bioelectromagnetism Volume: 15 Pages: 65-70
  • Peer Reviewed
• [Journal Article] RR-QT Interval Trend Covariability for Sudden Cardiac Death Risk Stratification (2012)
  • Author(s): Toshihiro Nishibe, Kei Sato, Kunihiro Yoshino, Ryota Seki, Kazuo Yana, and Takuya Ono
  • Journal Title: Proc. 34th Ann. Int. Conf. IEEE EMBS Volume: Proceedings Pages: 4287-4290
  • Peer Reviewed
• [Presentation] On the Evaluation of Instantaneous Heart Rate Reconstruction Accuracy (2014)
  • Author(s): Ichiro Joja, Naoto Higuchi, Kazuo Yana
  • Organizer: Ann. Int. Conf. IEEE Engineering in Medicine and Biology Soc.
  • Place of Presentation: 米国・シカゴ市
  • Year and Date: 2014-08-26 – 2014-08-30
• [Presentation] 糖尿病患者におけるＱＴ間隔の日内変動解析 (2012)
  • Author(s): 吉野邦弘、佐藤慶、八名和夫、小野卓哉
  • Organizer: 第51回日本生体医工学会大会
  • Place of Presentation: 九州大学（福岡県）
• [Presentation] 差分心拍スペクトルを用いた自律神経活動の状態分類 (2012)
  • Author(s): 安本豊、金子隼也、八名和夫
  • Organizer: 第51回日本生体医工学会大会
  • Place of Presentation: 九州大学（福岡県）
• [Presentation] 心臓突然死リスク評価指標としてのQT-RR間隔相関性 (2012)
  • Author(s): 西部俊広、関亮太、八名和夫、小野卓哉
  • Organizer: 第51回日本生体医工学会大会
  • Place of Presentation: 九州大学（福岡県）
• [Presentation] Individualized Autonomic State Classification based on Changes in Heart Rate Variability Indices
  • Author(s): Shunya Kaneko, Shohei Ymashita, and Kazuo Yana
  • Organizer: 52nd Annual conference of Japanese Society for Medical and Biological Engineering (JSMBE)
  • Place of Presentation: Osaka International Convention Center, Osaka, Japan
• [Presentation] Weighted Spline Smoothing Technique Applied to the Circadian Trend Estimation for QT Intervals of Diabetic Patients
  • Author(s): Kei Sato, Masaki Furuya, Kazuo Yana, and Takuya Ono
  • Organizer: 52nd Annual conference of Japanese Society for Medical and Biological Engineering (JSMBE)
  • Place of Presentation: Osaka International Convention Center, Osaka, Japan
• [Presentation] スプライン平滑化・カルマンフィルタを用いた心拍変動分析とその応用
  • Author(s): 八名和夫
  • Organizer: 第８回動的心電図研究会
  • Place of Presentation: 名古屋市立大学（愛知県）
  • Invited
• [Presentation] 相対心拍スペクトルを用いた自律神経活動状態の分類
  • Author(s): 山下翔平、金子隼也、八名和夫
  • Organizer: 第48回日本生体医工学会生体信号計測解釈研究会
  • Place of Presentation: 関東学院大学（神奈川県）
• [Presentation] 心臓突然死リスクとRRI日内変動の関係
  • Author(s): 樋口直人、西部俊広、八名和夫、小野卓也
  • Organizer: 第48回日本生体医工学会生体信号計測解釈研究会
  • Place of Presentation: 関東学院大学（神奈川県）
• [Presentation] 糖尿病患者における心電図QT-RR 間隔の共変性
  • Author(s): 古屋真己、佐藤慶、八名和夫、小野卓哉
  • Organizer: 第48回日本生体医工学会生体信号計測解釈研究会
  • Place of Presentation: 関東学院大学（神奈川県）