| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Outline of Final Research Achievements |
A light addressable potentiometric sensor (LAPS) is a method to detect a change of surface potential resulted from the adsorption of molecules as the change of the amplitude of photocurrent. This study was to extend the application of LAPS for medical diagnoses as a molecular interaction imaging device and a borderless multi-biosensor. I established the method to copy patterns of the protein on the LAPS sensor reproducibly to prove the usefulness of LAPS. With regard to the most important technique of surface modification of the sensor, I developed the methods of chemical modification and addition of surfactant to reinforce the electric charge of target molecules, because a LAPS detects the intrinsic electric charge of target molecules.
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