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Development of Wireless thermometer and heating unit for soft-heating hyperthermia treatment of malignant tumor.

Research Project

Project/Area Number 24500536
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionAkita University

Principal Investigator

MITOBE Kazutaka  秋田大学, 工学(系)研究科(研究院), 教授 (60282159)

Co-Investigator(Kenkyū-buntansha) SAITO Hajime  秋田大学, 医学系研究科, 准教授 (20323149)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywordsハイパーサーミア / 感温磁性体 / 低侵襲 / ガン治療 / 非接触温度計測 / ロボット / 温熱療法 / QOL / 深部温度計測
Outline of Final Research Achievements

Recently, the use of a ferromagnetic material in a soft-heating method has garnered much attention as a novel method for cancer treatment. By concurrently using this material as a thermal probe, we are currently developing a minimally-invasive heating and wireless temperature measurement system. We have found that by adjusting the distance between the heating coil and the material while maintaining a constant current flow in heating coil, the drift problem, which generated just after power is supplied during the on/off operation, did not occur any longer. Accordingly, it was not required the use of multi-sensors to reduce the drift, thereby minimizing costly. This study verified the validity of our wireless thermometry approach while performing rotary scanning and proposed a technique for determining achievement of target temperature. This knowledge complements other approaches for cancer treatment utilizing hyperthermia.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (19 results)

All 2015 2014 2013 2012

All Journal Article (9 results) (of which Peer Reviewed: 5 results,  Acknowledgement Compliant: 2 results) Presentation (9 results) (of which Invited: 1 results) Book (1 results)

  • [Journal Article] Rotary Scanning Wireless Temperature Measurement Method for Hyperthermia using Ferromagnetic Implants2015

    • Author(s)
      Loi Tonthat, Hajime Saito, Ryuhei Miyamoto, Masafumi Suzuki, Noboru Yoshimura, Kazutaka Mitobe
    • Journal Title

      IEEJ, TEEE A

      Volume: 10, suppliment

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Accuracy Improvement of Low-invasive Temperature Measurement for Hyperthermia Treatment using a Ferromagnetic Implant with Low Curie Temperature2014

    • Author(s)
      宮本 隆平,齊藤 元, 鈴木 雅史, 吉村 昇, 水戸部一孝
    • Journal Title

      IEEJ Transactions on Fundamentals and Materials

      Volume: 134 Issue: 7 Pages: 436-441

    • DOI

      10.1541/ieejfms.134.436

    • NAID

      130004438718

    • ISSN
      0385-4205, 1347-5533
    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Features of the Vision of Elderly Pedestrians when Crossing a Road2014

    • Author(s)
      Yasuhiro Matsui, Shoko Oikawa, Yoshio Aoki and Michiaki Sekine, Kazutaka Mitobe
    • Journal Title

      Stapp Car Crash Journal

      Volume: 58 Pages: 233-250

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An Attempt to Evaluate Postural Control with a Magnetic Motion Capture System2013

    • Author(s)
      工藤 香児、水戸部一孝、本田 耕平、石川 和夫
    • Journal Title

      Nippon Jibiinkoka Gakkai Kaiho

      Volume: 116 Issue: 10 Pages: 1106-1113

    • DOI

      10.3950/jibiinkoka.116.1106

    • NAID

      130003385765

    • ISSN
      0030-6622, 1883-0854
    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Inhibition of Hsp90 and 70 sensitizes melanoma cells to hyperthermia using ferromagnetic particles with a low Curie temperature2013

    • Author(s)
      Tomoyuki Miyagawa, Hajime Saito, Yoshihiro Minamiya, Kazutaka Mitobe, Shinogu Takashima, Naoko Takahashi, Aki Ito, Kazuhiro Imai, Satoru Motoyama, Junichi Ogawa
    • Journal Title

      International Journal of Clinical Oncology

      Volume: August 2013 Issue: 4 Pages: 722-730

    • DOI

      10.1007/s10147-013-0606-x

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development of a Ubiquitous Learning System for Dexterous Hand Operation2012

    • Author(s)
      K.Mitobe, M.Tomioka, M.Saito and M.Suzuki
    • Journal Title

      IEEE-ISMAR

      Volume: USB Pages: 299-300

    • DOI

      10.1109/ismar.2012.6402583

    • Related Report
      2012 Research-status Report
  • [Journal Article] Development of Pedestrian Simulator for the Prevention of Traffic Accidents Involving Elderly Pedestrians2012

    • Author(s)
      K.Mitobe, M.Suzuki and N.Yoshimura
    • Journal Title

      SICE Annual Conference 2012

      Volume: CD-ROM Pages: 1365-1368

    • Related Report
      2012 Research-status Report
  • [Journal Article] 歩行者事故予防に向けた高齢者の行動特性と道路横断タイミングに関する調査2012

    • Author(s)
      関根道昭,青木義郎,松井靖浩,及川昌子,水戸部一孝
    • Journal Title

      日本機械学会交通・物流部門大会講演論文集

      Volume: 21 Pages: 217-220

    • Related Report
      2012 Research-status Report
  • [Journal Article] 高周波磁場温熱療法におけるHsp70/90阻害薬併用の温熱増感作用に関する研究2012

    • Author(s)
      宮川智之,齋藤元,水戸部一孝,南谷佳弘,伊藤亜樹
    • Journal Title

      日本癌治療学会学術集会CD-ROM

      Volume: CD-ROM

    • Related Report
      2012 Research-status Report
  • [Presentation] Noise suppression method for wireless temperature measurement for hyperthermia Treatment using FILCT2014

    • Author(s)
      Mitobe, K., Miyamoto, R., Loi, T., T., Aki, F. and Saito, H.
    • Organizer
      Biomed. Eng. Int. Conf. 2014
    • Place of Presentation
      九州大学
    • Year and Date
      2014-11-26 – 2014-11-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 磁気式 MoCap を用いためまい患者の重症度定量評価方法の検討2014

    • Author(s)
      大渕光希,斉藤秀和,近江永豪,石川和夫,水戸部一孝
    • Organizer
      第 53 回日本生体医工学会大会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2014-06-24 – 2014-06-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 感温磁性体を利用したハイパーサーミアのための回転走査によるワイヤレス温度計測技術の精度向上2014

    • Author(s)
      TONTHAT LOI ,水戸部一孝,他
    • Organizer
      第 53 回日本生体医工学会大会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2014-06-24 – 2014-06-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 感温磁性体を利用したハイパーサーミアのためのワイヤレス温度計測システムの精度向上に関する研究2014

    • Author(s)
      安藝 史崇,水戸部一孝,他
    • Organizer
      第 53 回日本生体医工学会大会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2014-06-24 – 2014-06-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Drift Reduction Method of Induced Electromotive Force for Hyperthermia Using Ferromagnetic Particles2013

    • Author(s)
      R.Miyamoto, K.Mitobe, H.Saito, M.Suzuki, N.Yoshimura
    • Organizer
      35th Annual International IEEE EMBS Conference
    • Place of Presentation
      Osaka International Convention Center
    • Related Report
      2013 Research-status Report
  • [Presentation] Low Invasive Temperature Monitoring Method for Hyperthermia Using Induction Heating2013

    • Author(s)
      K.Mitobe, H.Saito, M.Suzuki, N.Yoshimura
    • Organizer
      35th Annual International IEEE EMBS Conference
    • Place of Presentation
      Osaka International Convention Center
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Hand‐MoCapデータを利用した多指ロボットハンドの関節角度算出方法の検討2012

    • Author(s)
      富岡雅弘,水戸部一孝,齋藤正親,鈴木雅史,吉村昇
    • Organizer
      バーチャルリアリティ学会大会
    • Place of Presentation
      慶應義塾大学
    • Related Report
      2012 Research-status Report
  • [Presentation] 歩行者事故予防に向けた高齢者の行動特性と道路横断タイミングに関する調査2012

    • Author(s)
      関根道昭,青木義郎,松井靖浩,及川昌子,水戸部一孝
    • Organizer
      日本機械学会交通・物流部門大会
    • Place of Presentation
      東京大学 生産技術研究所
    • Related Report
      2012 Research-status Report
  • [Presentation] 高周波磁場温熱療法におけるHsp70/90阻害薬併用の温熱増感作用に関する研究2012

    • Author(s)
      宮川智之,齋藤元,水戸部一孝,南谷佳弘,伊藤亜樹
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Research-status Report
  • [Book] 人間福祉工学ハンドブック2013

    • Author(s)
      水戸部一孝 他
    • Total Pages
      500
    • Publisher
      朝倉書店
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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