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Elucidation of Optimal Reconstruction Methods for Various Thoracic Defects

Research Project

Project/Area Number 24500553
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionKagawa University (2014)
Keio University (2012-2013)

Principal Investigator

NAGASAO Tomohisa  香川大学, 医学部, 准教授 (20245541)

Co-Investigator(Renkei-kenkyūsha) TAKANO Naoki  慶應義塾大学, 理工学部, 教授 (10206782)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsバイオメカニクス / シミュレーション / 胸郭 / 呼吸 / 有限要素法 / 腫瘍
Outline of Final Research Achievements

Treatment of thoracic defects is a challenging clinical issue. The present study elucidates the relationship between the locations of thoracic defects and loss of respiratory function. 10 sets of three-dimensional finite element models were produced from computed-tomography data of 10 persons, and categorized as Normal Type models. These models were modified by removing part of the thorax and categorized as Defect Type models. Varying the location of the defects, 6 types of Defect models were produced from each of the 10 Normal models; the defects were made on the anterior-superior, anterior-inferior, lateral-superior, lateral-inferior, posterior-superior, and posterior-inferior regions of the thorax. Among the 6 types of defect, the degree of functional loss was greatest with those defects on the lateral-inferior part of the thorax. Hence, in treating clinical cases where defects are expected to occur in this region, effort should be made to minimize the area of the defect.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (17 results)

All 2015 2014 2013 2012 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results,  Acknowledgement Compliant: 2 results) Presentation (4 results) Book (2 results) Remarks (4 results)

  • [Journal Article] Scoring of Deformed Costal Cartilages Reduces Postoperative Pain after Nuss Procedure for Pectus Excavatum2015

    • Author(s)
      Nagasao T, Hamamoto Y, Tamai K, Kogure T, Takano N, Tanaka Y
    • Journal Title

      Thoracic Cardiovascular Surgeon

      Volume: 未定

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Irregular Location of Major Pectoral Muscle Can Be a Causative Factor of Pectus Excavatum.2014

    • Author(s)
      4.Nagasao T, Shimizu Y, Morotomi K, Takano N, Jiang H, Kishi K.
    • Journal Title

      Medical Hypotheses.

      Volume: 82 Issue: 5 Pages: 512-517

    • DOI

      10.1016/j.mehy.2014.01.023

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Relationship between Locations of Thoracic Rib Defects and Loss of Respiratory Function-A Biomechanical Study2014

    • Author(s)
      Hatano A, Nagasao T (Corresponding Author), Cho Y, Shimizu Y, Takano N, Kaneko T, Kishi K.
    • Journal Title

      Thoracic and Cardiovascular Surgeon

      Volume: April

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A biomechanical study regarding the effect of tissue harvesting from the thorax on its movement during respiration2013

    • Author(s)
      Hatano A, Nagasao T(Corresponding Author), Shimizu Y, Jin H, Kaneko T, Cho Y, Jiang H, Kishi K.
    • Journal Title

      Computer-Aided Surgery

      Volume: 18 Issue: 5-6 Pages: 118-128

    • DOI

      10.3109/10929088.2013.777120

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relationship between Locations of Thoracic Rib Defects and Loss of Respiratory Function2013

    • Author(s)
      Hatano A, Nagasao T, Cho Y, Shimizu Y, Takano N, Kaneko T, Kishi K
    • Journal Title

      Thoracic and Cardiovascular Surgeon (ドイツ胸部外科学会誌)

      Volume: 印刷中

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] A biomechanical study regarding the effect of tissue harvesting from the thorax on its movement during respiration2013

    • Author(s)
      Hatano A, Nagasao T(Corresponding Author), Shimizu Y, Jin H, Kaneko T, Cho Y, Jiang H, Kishi K
    • Journal Title

      Computer-Aided Surgery

      Volume: 印刷中

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 胸郭の各種欠損が胸式呼吸の機能に及ぼす影響と、それを再建する意味についてのバイオメカニクス研究―胸郭再建のプロトコル作成に向けて2012

    • Author(s)
      永竿智久、清水雄介、畑野麻子、貴志和生
    • Journal Title

      日本形成外科学会会誌

      Volume: 32

    • NAID

      10031129802

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] Launching into the Ocean of "Cosmetic Thoracic Surgery"2014

    • Author(s)
      Nagasao T
    • Organizer
      Korea-Japan Academic Meeting of Plastic Surgery
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-05-15 – 2014-05-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] Laurnching into the Ocean of cosmetic Thoracic Surgery2014

    • Author(s)
      Nagasao T
    • Organizer
      The 12th Korean-Japan Conference of Plastic Surgery
    • Place of Presentation
      Inceon
    • Related Report
      2013 Research-status Report
  • [Presentation] Prediction of Post-Operative Thorax Shapes in Pectus Excavatum Surgery.2013

    • Author(s)
      Nagasao T
    • Organizer
      2013 European Association of Chest Wall Interest Group
    • Place of Presentation
      ソウル
    • Related Report
      2013 Research-status Report
  • [Presentation] 胸骨欠損が胸郭の呼吸機能に及ぼす影響に関するバイオメカニクス解析2013

    • Author(s)
      永竿智久
    • Organizer
      第56回日本形成外科学会総会・学術集会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Book] 形成外科:特集・シミュレーション外科2014

    • Author(s)
      永竿智久・野口昌彦・宮本純平・田中嘉雄
    • Total Pages
      8
    • Publisher
      克誠堂
    • Related Report
      2014 Annual Research Report
  • [Book] 躯幹の先天異常治療マニュアル2013

    • Author(s)
      野口昌彦
    • Total Pages
      106
    • Publisher
      全日本病院出版会
    • Related Report
      2012 Research-status Report
  • [Remarks] 香川大学形成外科 医学―工学 研究グループ

    • URL

      http://biomedical-engineering-research.org/index.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] 慶應義塾大学 医学―工学 研究グループ

    • URL

      http://biomedical-engineering-research.org/

    • Related Report
      2013 Research-status Report
  • [Remarks] 欠損を伴う胸郭が呈する、呼吸運動機能の定量的評価

    • URL

      http://biomedical-engineering-research.org/subject/index8.html

    • Related Report
      2012 Research-status Report
  • [Remarks] 慶應義塾大学形成外科 医学―工学 研究グループ

    • URL

      http://biomedical-engineering-research.org/member/index.html

    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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