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Analysis of mechanism on mirror therapy by functional brain imaging techniques

Research Project

Project/Area Number 24500567
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionHokkaido University

Principal Investigator

IKOMA Katsunori  北海道大学, 大学病院, 教授 (70202918)

Co-Investigator(Kenkyū-buntansha) MAKINO Hitoshi  北海道文教大学, 人間科学部, 准教授 (10583924)
Research Collaborator INAGAKI Yuji  北海道大学, 大学院医学研究科
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywordsミラーセラピー / 電気刺激 / 機能的近赤外線スペクトロスコピー / 運動観察 / 運動錯覚 / 筋電駆動型電気刺激 / ミラーニューロン / 上肢機能訓練 / 機能的近赤外分光法
Outline of Final Research Achievements

The present study investigated whether the combination of Mirror therapy (MT) which have been developed for patients with hemiplegia following stroke and Electrical stimulation (ES) modulated brain blood flow of healthy young subjects and elderly subjects. In young subjects, the brain blood flow of supramarginal gyrus corresponding to the stimulating hand by ES was increased comparing to rest in MT + ES task. On the other hand, in elderly subjects, the brain blood flow of precentral gyrus , postcentral gyrus, supramarginal gyrus, superior temporal gyrus, angular gyrus and middle frontal gyrus corresponding to the stimulating hand by ES was increased comparing to rest in MT + ES task. These results suggested that the combination of the visual input from mirror and synchronized movements by electrical stimulation elicited the effects of motor observation and motor kinesthesia illusion, and more facilitated these effects in elderly subjects with diminished proprioceptive sensation.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2014 2013 2012 Other

All Presentation (4 results)

  • [Presentation] Change of cerebral cortex excitability after Electromyogram triggered electrical stimulation combined with mirror visual feedback in healthy elderly subjects2014

    • Author(s)
      Yuji Inagaki,Kazunori Seki,Hitoshi Makino,Daisuke Sawamura,Katsunori Ikoma
    • Organizer
      30th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Estrel Hotel & Convention Center Berlin (ベルリン,ドイツ)
    • Related Report
      2013 Research-status Report
  • [Presentation] 健常高齢者における筋電駆動型電気刺激を用いた電気的な運動と鏡からの視覚入力が大脳皮質に与える影響2013

    • Author(s)
      稲垣侑士,関和則,牧野均,浦上祐司,松尾雄一郎,宮本環,生駒一憲
    • Organizer
      第43回日本臨床神経生理学会学術大会
    • Place of Presentation
      三翠園(高知市)
    • Related Report
      2013 Research-status Report
  • [Presentation] Change of serebral cortex excitability after EMG triggered FES combined with mirror therapy in healthy subjects2012

    • Author(s)
      Yuji Inagaki, Katsunori Ikoma, Yuji Urakami, Hitoshi Makino, Kazunori Seki
    • Organizer
      International Society of Electrophysiology and Kinesiology Conference 2012
    • Place of Presentation
      Brisbane Convention and Exhibition Centre (Australia)
    • Related Report
      2012 Research-status Report
  • [Presentation] ミラーセラピーの神経メカニズムと電気刺激を用いた新たな治療法

    • Author(s)
      稲垣侑士,関和則,牧野均,宮本環,生駒一憲
    • Organizer
      第44回北海道作業療法学会
    • Place of Presentation
      アクセスサッポロ(札幌市)
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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