Rehabilitation and the markers for its evaluation in rheumatoid arthritis
| Project/Area Number |
24500592
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Nagasaki University |
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Principal Investigator |
ORIGUCHI Tomoki 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (90295105)
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| Co-Investigator(Kenkyū-buntansha) |
KAWASHIRI Shinya 長崎大学, 医歯薬学総合研究科(医学系), 助教 (20457576)
OKITA Minoru 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (50244091)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | リハビリテーション / 関節リウマチ / サイトカイン / 神経ペプチド / 超音波検査 |
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| Outline of Final Research Achievements |
In rehabilitation of rheumatoid arthritis patients, exercise therapy, gymnastics, and physical therapy were performed. CRP,DAS28-CRP,and IL-6 were improved by exercise therapy. Tender joint number, DAS-CRP, and IL-6 were improved by gymnastics. Tender joint number, pain VAS, and mHAQ were improved by physical therapy. In excercise therapy, a significant correlation was seen in IL-6 and a change of DAS28-CRP, and it was suggested that IL-6 was a useful marker for evaluation of excercise therapy. Althou there was not seen a significant improvement of the articular lesion in joint sonography, the observation was useful for monitering that rehabilitation was performed safely.
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Report
(4 results)
Research Products
(33 results)
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[Journal Article] Synovial inflammation assessed by ultrasonography correlates with MRI-proven osteitis in patients with rheumatoid arthritis.2014
Author(s)
Kawashiri SY, Suzuki T, Nakashima Y, Horai Y, Okada A, Nishino A, Iwamoto N, Ichinose K, Arima K, Tamai M, Nakamura H, Origuchi T, Uetani M, Aoyagi K, Eguchi K, Kawakami A.
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Journal Title
Rheumatology (Oxford).
Volume: -
Issue: 8
Pages: 1452-1456
DOI
Related Report
Peer Reviewed
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[Journal Article] Ultrasonographic examination of rheumatoid arthritis patients who are free of physical synovitis: power Doppler subclinical synovitis is associated with bone erosion.2014
Author(s)
Kawashiri SY, Suzuki T, Nakashima Y, Horai Y, Okada A, Iwamoto N, Ichinose K, Tamai M, Arima K, Nakamura H, Origuchi T, Uetani M, Aoyagi K, Eguchi K, Kawakami A.
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Journal Title
Rheumatology (Oxford).
Volume: 53
Issue: 3
Pages: 562-569
DOI
NAID
Related Report
Peer Reviewed
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[Journal Article] 関節リウマチ患者におけるエタネルセプト治療による関節超音波所見の改善2013
Author(s)
川尻 真也, 鈴木 貴久, 中島 好一, 寶來 吉朗, 岩本 直樹, 一瀬 邦弘, 中村 英樹, 川上 純, 玉井 慎美, 折口 智樹, 有馬 和彦, 青柳 潔
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Journal Title
九州リウマチ
Volume: 33
Pages: 15-21
Related Report
Peer Reviewed
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[Journal Article] 関節リウマチ患者における抗リウマチ薬治療による関節超音波パワードプラスコアと血管新生因子血清濃度の改善2013
Author(s)
川尻 真也, 鈴木 貴久, 中島 好一, 寶來 吉朗, 岩本 直樹, 一瀬 邦弘, 中村 英樹, 川上 純, 玉井 慎美, 折口 智樹, 有馬 和彦, 青柳 潔：
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Journal Title
九州リウマチ
Volume: 33
Pages: 74-80
Related Report
Peer Reviewed
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[Journal Article] Musculoskeletal ultrasonography assists the diagnostic performance of the 2010 classification criteria for rheumatoid arthritis2013
Author(s)
Kawashiri SY, Suzuki T, Okada A, Yamasaki S, Tamai M, Nakamura H, Origuchi T, Mizokami A, Uetani M, Aoyagi K, Eguchi K, Kawakami A
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Journal Title
Modern Rheumatology
Volume: 23
Pages: 36-43
NAID
Related Report
Peer Reviewed
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[Journal Article] Significant improvement in MRI-proven bone edema is associated with protection from structural damage in very early RA patients managed using the tight control approach2013
Author(s)
Kita J, Tamai M, Arima K, Kawashiri SY, Horai Y, Iwamoto N, Okada A, Koga T, Nakashima Y, Suzuki T, Yamasaki S, Nakamura H, Origuchi T, Ida H, Aoyagi K, Uetani M, Eguchi K, Kawakami A
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Journal Title
Modern Rheumatology
Volume: 23
Pages: 254-259
NAID
Related Report
Peer Reviewed
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