| Project/Area Number |
24500833
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAYAMA MIYUKI 大阪府立大学, 看護学部, 教授 (70327451)
KAWAUCHI HIROHITO 北里大学, 医学部, 講師 (90152917)
ORISAKA MAKOTO 福井大学, 医学部, 講師 (80324143)
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| Research Collaborator |
ASADA YOSHIMASA
SHIOTANI MASAHIDE
ODAWARA YASUSHI
YOSHIDA HIROAKI
MIO YASUYUKI
MINOURA HIROYUKI
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 卵巣予備能 / Anti－Mullerioan Hormone / normograms / 生活習慣 / 世代間妊孕性 / 健康女性 / AMH / AMHnormograms / 月経異常 / 甲状腺疾患 / コーヒー / 肥満 / 不妊女性 / 年齢 / 婦人科疾患 / 既往歴 / 母親の不妊治療歴 |
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| Outline of Final Research Achievements |
PURPOSE: The aim of this study is to establish educational support for infertility treatment by clarifying the characteristics of age-related changes in ovarian reserve of Japanese women in treatment.METHODS:Participants were 2,325 infertile Japanese women (with the exclusion of those who were diagnosed as having PCO) from 6 reproductive medical centers.RESULTS:Age-related normograms in Japanese women for the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles of AMH levels were produced. AMH levels and correlation between age and different percentiles of AMH were used to create a fitted curve. The data for the AMH levels by age for the 3rd to 50th ercentiles showed a gradual decrease, whereas the results for the 75th percentiles and greater.Drinking coffee daily was significantly associated with AMH levels (p < .001) and multiple regression analysis indicated that total R2 was 007 (p = .002). showed a rapid decline.
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