| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
Oxidative stress plays important roles in pathophysiology of atherosclerotic disease. We assessed the hypothesis that combined aerobic and resistance exercise training decrease oxidative stress in patient with cardiovasucular disease(CVD).
In combined resistance and aerobic exercise (AE+RE) group, d-ROMs (index of reactive oxygen species) decreased and BAP (index of antioxidant) significantly increased. Consequently BAP/d-ROMs ratio (index of oxidative stress) significantly increased after training period. BAP/d-ROMs ratio in the AE+RE group were significantly higher than those in the aerobic exercise (AE) group after training period. Conclusions: The present findings suggest that combined aerobic and resistance exercise training decrease oxidative stress by augmenting antioxidant potential in patients with CVD. Thus, combined aerobic exercise and low grade resistance exercise training have potential role for prevention of CVD.
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