| Project/Area Number |
24500956
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Doshisha Women's College of Liberal Arts |
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Principal Investigator |
MURAKAMI Megumi 同志社女子大学, 生活科学部, 准教授 (80340769)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | 葉酸 / 抗酸化性 / 血栓溶解性 / ヒトさい帯静脈血管内皮細胞 / アスパラガス / ビタミンB12 / 過酸化水素 / Huvec / 細胞生存率 / 血管内皮細胞 |
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| Outline of Final Research Achievements |
Standards of folic acid has been shown to have antioxidant properties, folic acid contained in foods was also revealed to have similar anti-oxidative properties. Its antioxidant is to be exerted against oxidative damage of vascular endothelial cells was suggested, the effect was weak.
In terms of stroke prevention, we examined the thrombolytic properties of folic acid using the fibrin plate method is a thrombosis model. As a result, were observed thrombolytic the standards of folic acid. However, thrombolytic was observed in folic acid that is extracted from asparagus. Thus, may show some effect on thrombus folic acid contained in the food has been suggested.
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