| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
We examine the influence on the medicinal effect or clinical condition of the simultaneous intake of functional food ingredients and drugs. First, we investigated the combination of antihypertensive drug and sardine peptide in spontaneously hypertensive rats. Because both of them have antihypertensive action by ACE inhibition. As a result, we could not find any alteration on the medicinal effect and clinical condition by the simultaneous intake of drug and functional food ingredients with similar mechanism of action. In addition, we examine the influence of medium-chain fatty acid on clinical condition in the type 1 and 2 diabetes animal models. Interestingly, in the type 1 animal models, we did not find the significant increase of blood ketone body and observed the survival advantage by the intake of medium-chain fatty acid compared with commercially available dietary oil.
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