| Project/Area Number |
24501028
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Department of Clinical Research, National Hospital Organization Kyoto Medical Center |
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Principal Investigator |
TSUZAKI Kokoro 独立行政法人国立病院機構(京都医療センター臨床研究センター), 臨床研究企画運営部, 研究員 (80450881)
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| Co-Investigator(Kenkyū-buntansha) |
SAKANE Naoki 独立行政法人国立病院機構(京都医療センター臨床研究センター), 臨床研究企画運営部, 研究室長(予防医学) (40335443)
KOTANI Kazuhiko 自治医科大学, 医学部, 准教授 (60335510)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 時間栄養学 / 脂質代謝 / 生活習慣病 / 食事指導 / 予防医学 |
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| Outline of Final Research Achievements |
We investigated the relationships among eating schedule, lipoprotein metabolisms (small dense LDL; sdLDL), and the CLOCK 3111T/C polymorphism in women with dyslipidemia. In carriers of T/T homozygotes, the area of sdLDL was slightly higher than that in carriers of the C alleles (T/C or C/C). As carriers of T/T homozygotes had breakfast earlier, their morning fasting time was shorter than carriers of the C alleles.
Interventions were performed simultaneously in rotating shift and day shift groups to assess whether the group-based lifestyle intervention affects body weight in male shift workers. There was no difference in body weight between the 2 groups before the intervention; however, weight loss was significantly smaller in the rotating shift group than that in day shift groups after the intervention.
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