| Project/Area Number |
24510069
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Mie University |
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Principal Investigator |
NISHIMURA Yuhei 三重大学, 医学(系)研究科(研究院), 准教授 (30303720)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Toshio 三重大学, 大学院医学系研究科, 教授 (00135443)
SHIMADA Yasuhito 三重大学, 大学院医学系研究科, 助教 (40378427)
UMEMOTO Noriko 三重大学, 大学院医学系研究科, 助教 (40649365)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 放射線 / 発達神経毒性 / 行動解析 / 治療薬 / スクリーニング / ゼブラフィッシュ / 放射線影響評価 / 蛍光生体イメージング |
|---|
| Outline of Final Research Achievements |
The developing brain is extremely sensitive to irradiation. Irradiation during development has been implicated in various neuropsychiatric and neurological disorders. In this study, we were able to develop zebrafish-based behavior assay to detect subtle but significant developmental neurotoxicity of irradiation and to identify chemicals protective to the developmental neurotoxicity of irradiation.
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