| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2015: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
We found introns that are shorter than previously expected and published them as “ultra-short introns.”
Because exon/intron boundary is dynamically defined, we evaluated the ultra-short introns using transcript and genome sequences of vertebrate species as well as human. We found seven orthologous ultra-short introns in experimentally validated transcript sequences. In case of other ultra-short introns, few transcript sequences are available in non-human species. Moreover, splice di-nucleotides sequences of these ultra-short introns scarcely conserved in genome sequences. These results suggest that at least some of ultra-short introns have been appeared within human or closely related species and/or are specifically expressed depending on cell types or development stages.
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