• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

New development of applications of branching process and stochastic equation to mathematica;l medicine.

Research Project

Project/Area Number 24540114
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General mathematics (including Probability theory/Statistical mathematics)
Research InstitutionSaitama University

Principal Investigator

DOKU Isamu  埼玉大学, 教育学部, 教授 (60207686)

Project Period (FY) 2012-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords分枝過程 / 測度値マルコフ過程 / 数理医学 / 局所消滅性 / 腫瘍免疫 / 数理モデル / 環境依存型モデル / 超過程 / 免疫能の飽和性 / 生存性・共存性 / 腫瘍免疫応答 / 確率微分方程式 / ガン血管新生 / 応用確率論 / 分枝マルコフ過程 / 確率方程式 / 免疫応答
Outline of Final Research Achievements

We propose an environment-dependent model that is able to describe immune responses of effector group against canceer cells. This model is capable of expressing state transition according to the competition between cancer cells and neighboring immune effects. Scaling limit procedure produces a superprocess, and we investigate the limiting process precisely, with the result that (1) survival of normal cells depends greatly on the parameter of the system; (2) tendency toward cancer depends on the dimension of the system, for instance, it proves to be always cancerous in one dimension, and it heavily depends on the probabilistic property of the system in higher dimensions, and either it has tendency toward cancer or it becomes definitely cancerous according to the Markov property of the system.

Report

(6 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (53 results)

All 2017 2016 2015 2014 2013 2012 Other

All Journal Article (28 results) (of which Open Access: 16 results,  Acknowledgement Compliant: 19 results,  Peer Reviewed: 2 results) Presentation (22 results) (of which Invited: 3 results) Book (3 results)

  • [Journal Article] A support problem for superprocesses in terms of random measure.2017

    • Author(s)
      I. Doku
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 2030 Pages: 108-115

    • Related Report
      2016 Annual Research Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] 超過程に関するコンパクト性について2017

    • Author(s)
      道工 勇
    • Journal Title

      ISM Cop.Res. Rept.

      Volume: 385 Pages: 80-87

    • Related Report
      2016 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] An estimate of survival probability for superprocesses.2017

    • Author(s)
      I. Doku
    • Journal Title

      J. SUFE Math. Nat. Sci.

      Volume: 66-1 Pages: 259-263

    • Related Report
      2016 Annual Research Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] A recursive inequality of empirical measures associated with EDM.2016

    • Author(s)
      I. Doku
    • Journal Title

      J. SUFE Math. Nat. Sci.

      Volume: 65-2 Pages: 253-259

    • Related Report
      2016 Annual Research Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] ガン免疫と環境依存型モデル2016

    • Author(s)
      道工 勇
    • Journal Title

      日本応用数理学会論文誌

      Volume: 26-2 Pages: 213-252

    • NAID

      130005169997

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Applications of environment-dependent models to tumor immunity.2016

    • Author(s)
      I. Doku
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 1994 Pages: 68-74

    • Related Report
      2016 Annual Research Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] An example for convergence of environment-dependent spatial models.2016

    • Author(s)
      Isamu DOKU
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 65-1 Pages: 179-186

    • Related Report
      2015 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Integral equation and unbiased estimator.2015

    • Author(s)
      Isamu DOKU
    • Journal Title

      ISM Cop. Res. Rept.

      Volume: 350 Pages: 68-73

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Une remarque sur le processus de semimartingale dans un probleme de Skorokhod.2015

    • Author(s)
      Isamu DOKU
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 64-1 Pages: 163-171

    • Related Report
      2015 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Construction of probablistic solutions to deterministic integral equations with a nonlinear term.2015

    • Author(s)
      Isamu DOKU
    • Journal Title

      Proc. 2015 Math. Sci. Symp. ISMA

      Volume: 1 Pages: 34-37

    • Related Report
      2015 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] Some integral equation related to a branching model.2015

    • Author(s)
      Isamu DOKU
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 1937 Pages: 25-31

    • Related Report
      2015 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Approximation of random wave phenomenon in terms of heat conductive model.2015

    • Author(s)
      Isamu DOKU
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 64-2 Pages: 225-241

    • Related Report
      2015 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Unbiased estimator as asolution to integral equation.2015

    • Author(s)
      Isamu DOKU
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 1952 Pages: 1-8

    • Related Report
      2015 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] The limit function and characterization equation for fluctuation in the tumour angiogenic SDE model.2014

    • Author(s)
      I. Doku and M. Misawa
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 63(1) Pages: 115-131

    • Related Report
      2014 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] On a probabilistic solution for a class of integral equations.2014

    • Author(s)
      I. Doku
    • Journal Title

      ISM Cop. Res. Rept.

      Volume: 328 Pages: 56-61

    • Related Report
      2014 Research-status Report 2013 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Star-product functional and unbiased estimator of solutions to nonlinear integral equations.2014

    • Author(s)
      I. Doku
    • Journal Title

      Far East J. Math. Sci.

      Volume: 89 Pages: 69-128

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Probabilistic construction of solutions to some integral equations.2014

    • Author(s)
      I. Doku
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 1903 Pages: 23-29

    • Related Report
      2014 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Star-product functional and related integral equations.2014

    • Author(s)
      I. Doku
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 63(2) Pages: 181-188

    • Related Report
      2014 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] Vessel mathematical model for tumour angiogenesis and its fluctuation characterization equation.2014

    • Author(s)
      I. Doku
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 1917 Pages: 29-36

    • Related Report
      2014 Research-status Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] The limit function and characterization equation for fluctuation in the tumour angiogenic SDE model.2014

    • Author(s)
      Isamu DOKU and Mikako MISAWA
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 63-1 Pages: 115-131

    • Related Report
      2013 Research-status Report
  • [Journal Article] Extinction of historical superprocess associated with stable random measure.2013

    • Author(s)
      Isamu DOKU
    • Journal Title

      ISM Cop.Res. Rept.

      Volume: 300 Pages: 97-104

    • Related Report
      2013 Research-status Report
  • [Journal Article] On a class of historical superprocess in the Dynkin sense.2013

    • Author(s)
      Isamu DOKU
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 62-1 Pages: 249-266

    • Related Report
      2013 Research-status Report
  • [Journal Article] Finite time extinction of stochastic model for tumour immunity.2013

    • Author(s)
      Isamu DOKU
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 1853 Pages: 199-201

    • Related Report
      2013 Research-status Report
  • [Journal Article] Finite time extinction of historical superprocess related to stable measure.2013

    • Author(s)
      Isamu DOKU
    • Journal Title

      RIMS Kokyuroku (Kyoto Univ.)

      Volume: 1855 Pages: 1-9

    • Related Report
      2013 Research-status Report
  • [Journal Article] Mean principle and fluctuation of SDE model for tumour angiogenesis.2013

    • Author(s)
      Isamu DOKU and Mikako MISAWA
    • Journal Title

      J. Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: 62-2 Pages: 183-206

    • Related Report
      2013 Research-status Report
  • [Journal Article] Extinction of historical superprocess associated with stable random measure.2013

    • Author(s)
      Isamu DOKU
    • Journal Title

      ISM Rept

      Volume: Volume 300 Pages: 97-104

    • Related Report
      2012 Research-status Report
  • [Journal Article] On a class of historical superprocesses in the Dynkin sense.2013

    • Author(s)
      Isamu DOKU
    • Journal Title

      J. of Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: Volume 62, No.1 Pages: 249-266

    • Related Report
      2012 Research-status Report
  • [Journal Article] On extinction of measure-valued Markov processes.2012

    • Author(s)
      isamu DOKU
    • Journal Title

      J. of Saitama Univ. Fac. Educ. Math. Nat. Sci.

      Volume: Volume 61, no.2 Pages: 155-172

    • Related Report
      2012 Research-status Report
  • [Presentation] ランダム測度に依る超過程のコンパクト台について2017

    • Author(s)
      道工 勇
    • Organizer
      日本数学会
    • Place of Presentation
      首都大学東京(東京都, 八王子市)
    • Year and Date
      2017-03-24
    • Related Report
      2016 Annual Research Report
  • [Presentation] 環境依存型モデルの腫瘍免疫への応用2015

    • Author(s)
      道工 勇
    • Organizer
      日本数理生物学会
    • Place of Presentation
      京都大学数理解析研究所(京都府京都市)
    • Year and Date
      2015-11-24
    • Related Report
      2015 Research-status Report
  • [Presentation] ガン免疫と環境依存型モデル2015

    • Author(s)
      道工 勇
    • Organizer
      日本応用数理学会
    • Place of Presentation
      金沢大学角間キャンパス(石川県金沢市)
    • Year and Date
      2015-09-07
    • Related Report
      2015 Research-status Report
  • [Presentation] ある積分方程式に関連する不偏推定量2015

    • Author(s)
      道工 勇
    • Organizer
      日本数学会
    • Place of Presentation
      明治大学駿河台キャンパス(東京都・千代田区)
    • Year and Date
      2015-03-21 – 2015-03-24
    • Related Report
      2014 Research-status Report
  • [Presentation] 非線形項をもつ確定的積分方程式に対する確率解の構成2015

    • Author(s)
      道工 勇
    • Organizer
      国際理科学協会
    • Place of Presentation
      大阪国際大学・枚方キャンパス(大阪府・枚方市)
    • Year and Date
      2015-03-14
    • Related Report
      2014 Research-status Report
  • [Presentation] ある確定的積分方程式の確率解の構成2014

    • Author(s)
      道工 勇
    • Organizer
      日本数学会
    • Place of Presentation
      広島大学(広島県・東広島市)
    • Year and Date
      2014-09-25 – 2014-09-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 分枝モデルの積分方程式への応用2014

    • Author(s)
      道工 勇
    • Organizer
      日本応用数理学会
    • Place of Presentation
      政策研究大学院大学(東京都・港区)
    • Year and Date
      2014-09-03 – 2014-09-05
    • Related Report
      2014 Research-status Report
  • [Presentation] ガン血管新生の数理モデルに関するゆらぎ解析2013

    • Author(s)
      道工 勇
    • Organizer
      日本応用数理学会
    • Place of Presentation
      アクロス福岡(福岡県福岡市)
    • Related Report
      2013 Research-status Report
  • [Presentation] ガン血管新生に関する数理モデル2013

    • Author(s)
      道工 勇
    • Organizer
      日本数理生物学会
    • Place of Presentation
      静岡大学工学部(浜松キャンパス)
    • Related Report
      2013 Research-status Report
  • [Presentation] ある積分方程式の解の確率表現2013

    • Author(s)
      道工 勇
    • Organizer
      科研費研究集会「確率解析とその周辺」
    • Place of Presentation
      京都大学総合人間学部
    • Related Report
      2013 Research-status Report
  • [Presentation] ある積分方程式の確率解について2013

    • Author(s)
      道工 勇
    • Organizer
      統計数理研究所・共同研究集会
    • Place of Presentation
      統計数理研究所(東京都立川市)
    • Related Report
      2013 Research-status Report
  • [Presentation] ガン血管新生の脈管数理モデルとゆらぎ特徴付け方程式2013

    • Author(s)
      道工 勇
    • Organizer
      京都大学数理解析研究所・共同研究
    • Place of Presentation
      京都大学数理解析研究所
    • Related Report
      2013 Research-status Report
  • [Presentation] ある積分方程式の解の確率論的構成2013

    • Author(s)
      道工 勇
    • Organizer
      科研費研究集会
    • Place of Presentation
      京都大学数理解析研究所
    • Related Report
      2013 Research-status Report
  • [Presentation] Recent development of WNA applied to stochastic equations.2013

    • Author(s)
      Isamu DOKU
    • Organizer
      International Workshop on Infinite Dimensional Analysis, Quantum Probability and Statistics
    • Place of Presentation
      愛知県立大学
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Extinction of superprocess related to stable random measure.2012

    • Author(s)
      Isamu DOKU
    • Organizer
      The 2nd IMS-APRM International Conference 2012 Tsukuba
    • Place of Presentation
      つくば国際会議場
    • Related Report
      2012 Research-status Report
  • [Presentation] 腫瘍免疫に関する確率モデルの有限時間消滅性2012

    • Author(s)
      道工 勇
    • Organizer
      日本数理生物学会・第22回大会
    • Place of Presentation
      岡山大学
    • Related Report
      2012 Research-status Report
  • [Presentation] ランダム測度に付随するヒストリカル超過程2012

    • Author(s)
      道工 勇
    • Organizer
      研究集会「確率解析とその周辺」
    • Place of Presentation
      名古屋大学大学院多元数理研究科
    • Related Report
      2012 Research-status Report
  • [Presentation] 安定ランダム測度に付随する経歴超過程の消滅性2012

    • Author(s)
      道工 勇
    • Organizer
      共同研究「無限分解可能過程に関する諸問題XVII」
    • Place of Presentation
      統計数理研究所(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] 腫瘍免疫確率モデルの有限時間消滅性2012

    • Author(s)
      道工 勇
    • Organizer
      研究集会「第9回生物数学の理論とその周辺」
    • Place of Presentation
      京都大学・数理解析研究所
    • Related Report
      2012 Research-status Report
  • [Presentation] 安定測度に関連するヒストリカル超過程の有限時間消滅性2012

    • Author(s)
      道工 勇
    • Organizer
      共同研究「確率論シンポジウム」
    • Place of Presentation
      京都大学・数理解析研究所
    • Related Report
      2012 Research-status Report
  • [Presentation] がん細胞に対する免疫応答の確率モデルと消滅性

    • Author(s)
      道工 勇
    • Organizer
      文部科学省特別経費プロジェクト「脳と末梢セミナー」
    • Place of Presentation
      埼玉大学・研究機構棟
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] がんの免疫応答の数理

    • Author(s)
      道工 勇
    • Organizer
      科学者の芽育成プログラム・冬休み集中講座
    • Place of Presentation
      埼玉大学・総合研究棟
    • Related Report
      2012 Research-status Report
    • Invited
  • [Book] Limit Theorems for Superprocesses.2014

    • Author(s)
      I. Doku
    • Total Pages
      120
    • Publisher
      Schalt. Lange
    • Related Report
      2014 Research-status Report
  • [Book] Limit theorems for superprocesses: rescaled processes, immigration superprocesses and homogeneous superprocesses.2014

    • Author(s)
      Isamu DOKU
    • Total Pages
      118
    • Publisher
      LAP Schaltungsdienst Lange o.H.G. (Berlin)
    • Related Report
      2013 Research-status Report
  • [Book] 確率と統計2012

    • Author(s)
      道工 勇
    • Total Pages
      458
    • Publisher
      数学書房
    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi