Application of probability theory to the generation of double-strand breaks of DNA
| Project/Area Number |
24540128
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General mathematics (including Probability theory/Statistical mathematics)
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| Research Institution | Hiroshima University |
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Principal Investigator |
SAISHO Yasumasa 広島大学, 工学(系)研究科(研究院), 准教授 (70195973)
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| Co-Investigator(Kenkyū-buntansha) |
KANAGAWA Shuya 東京都市大学, 共通教育部, 教授 (50185899)
HATAUE Itaru 金沢大学, 理工学域電子情報学系, 教授 (50218476)
ITO Atsushi 東海大学, 工学部, 教授 (80193473)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 確率モデル / ＤＮＡ / ２本鎖切断 / 放射線量 / 線エネルギー付与 / 2本鎖切断(dsb) / 放射線量依存性 / 線エネルギー付与 (LET) / DNA / ２本鎖切断(dsb) |
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| Outline of Final Research Achievements |
First, we got the dose dependence of the generation of DNA double-strand breaks (dsbs) by constructing stochastic models and published a paper of this results.
Next, we considered the double dependence of the generation of dsbs on dose and linear energy transfer (LET) by extending our previous mathematical models.
We also found that the theory of hitting times of a Brownian motion is deeply related to this problem.
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Report
(4 results)
Research Products
(53 results)
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[Presentation] S-continuous financial time series composed from the delta-function2014
Author(s)
S. Kanagawa
Organizer
The 10th AIMS Conference on Dynamical Systems, Differential Equations and Applications, Special Session 129: Qualitative and Quantitative Techniques for Differential Equations Arising in Economics
Place of Presentation
Universidad Autonoma de Madrid, Madrid, Spain
Year and Date
2014-07-07 – 2014-07-11
Related Report
Invited
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[Presentation] Optimal portfolios based on weakly dependent data2014
Author(s)
S. Kanagawa
Organizer
The 10th AIMS Conference on Dynamical Systems, Differential Equations and Applications, Special Session 129: Qualitative and Quantitative Techniques for Differential Equations Arising in Economics
Place of Presentation
Universidad Autonoma de Madrid, Madrid, Spain
Year and Date
2014-07-07 – 2014-07-11
Related Report
Invited
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[Book] 数理工学社2014
Author(s)
畑上 到
Total Pages
232
Publisher
工学基礎 フーリエ解析とその応用[新訂版]
Related Report
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