Dynamics of inhomogeneous structures in biomembranes
| Project/Area Number |
24540439
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biophysics/Chemical physics
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SEKI Kazuhiko 独立行政法人産業技術総合研究所, ナノシステム研究部門, 主任研究員 (60344115)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | ソフトマター / 生体膜 / 膜タンパク質 / ブラウン運動 / 異常拡散 / マイクロレオロジー |
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| Outline of Final Research Achievements |
In the raft model, dynamical heterogeneity occurring in multi-component lipid membranes plays an essential role. The problems that we have tackled involve (i) anomalous lateral diffusion in a viscous membrane surrounded by viscoelastic media, (ii) growth kinetics of circular liquid domains on vesicles by diffusion-controlled coalescence, (iii) diffusion coefficients in leaflets of bilayer membranes, (iv) drag coefficient of a rigid spherical particle in a near-critical binary fluid mixture, (v) budding of domains in mixed bilayer membranes, (vi) relaxation dynamics of binary lipid bilayers. As an outcome of our investigations, we have proposed a new method called membrane microrhelogy.
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Report
(4 results)
Research Products
(30 results)
