| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Outline of Final Research Achievements |
Calcium phosphate cements are cinically used for bone reconstruction. However, the set cement has higher Young's modulus than natural bone. Therefore bone reabsorption is liable to occur due to stress shielding. The present study aimed at prepraration organically modified bone cements and investigation of the effect of the modification on setting properties, mechanical properties and bone affinity. It was found that dental glass ionomer cement can be developed by addition of polyglutamic acid, and that ability of bone integration of PMMA bone cement can be improved by modification with phosphate-containing organic compounds without significant deterioration of mechanical properties.
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