Investigation of electric induced flow and particle movement under Applied Alternating Current Electric Field to Develop Nano-scale cell surgery
| Project/Area Number |
24560203
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Fluid engineering
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 細胞操作 / 流動制御 / 電場誘起流動 / 交流電場 / 細胞治療 / 細胞手術 / 誘電特性 / 誘電泳動 / エレクトロポレーション / マイクロ流動 |
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| Outline of Final Research Achievements |
A manipulation of cells is important technique to improve medical technology for cell transplantation and regenerative medicine. Furthermore this technique can be used for nano-scale surgery to maintain cell condition and cell properties. Controlling particle migration and flow with a micro sharp electrode using alternating current electric filed has several potential to develop cell manipulation device. And this device can provide a low invasive electroporation to maintain the cell properties. This device is useful for the cell manipulation and it is easy to control cells with their dielectric properties. In this study, a confirmation of the shape tip electrode for the cell manipulation under AC electric field was introduced and the cells and particles velocity near the electrode tip under several conductivity conditions were measured to investigate the flow structure and the cell movement around the electrode with experimental approach and analytical approach.
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Report
(4 results)
Research Products
(11 results)
