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Production of calcium phosphate on titanium from a simulated body fluid flowing in a confined space

Research Project

Project/Area Number 24560821
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Inorganic materials/Physical properties
Research InstitutionNiigata University

Principal Investigator

KIMURA ISAO  新潟大学, 自然科学系, 教授 (00169921)

Co-Investigator(Kenkyū-buntansha) TAGUCHI Yoshinari  新潟大学, 自然科学系, 准教授 (30293202)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsリン酸カルシウム / チタン / 疑似体液 / 流動 / 化学工学
Outline of Final Research Achievements

A small reactor involving a confined space was fabricated, in which calcium phosphate (CaP) was produced on titanium by flowing a simulated body fluid (SBF). The mixing characteristics in the reactor were evaluated by the impulse response testing. The relationship between the intermittently flowing conditions of SBF and the CaP yield was discussed. The crystalline phase of the product was identified as calcium-deficient hydroxyapatite. It was found that dispersion intensity is useful as an evaluation index of mixing characteristics instead of dispersion number used in general. The production of CaP was accelerated at larger dispersion intensity more than static condition. The knowledge on the effects of the SBF composition was also obtained.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (10 results)

All 2014 Other

All Presentation (10 results) (of which Invited: 1 results)

  • [Presentation] リン酸カルシウム系化合物の生成に及ぼす疑似体液の間欠流通間隔および流速の影響2014

    • Author(s)
      佐藤裕昭, 田口佳成, 木村勇雄
    • Organizer
      化学工学会新潟大会
    • Place of Presentation
      新潟大学(新潟県)
    • Year and Date
      2014-11-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] チタン上でのリン酸カルシウム生成に及ぼす水溶液組成の影響2014

    • Author(s)
      鈴木浩正, 木村勇雄
    • Organizer
      化学工学会新潟大会
    • Place of Presentation
      新潟大学(新潟県)
    • Year and Date
      2014-11-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 回転反応器中におけるチタン上でのリン酸カルシウム化合物の生成2014

    • Author(s)
      岡村 駿, 木村勇雄
    • Organizer
      化学工学会新潟大会
    • Place of Presentation
      新潟大学(新潟県)
    • Year and Date
      2014-11-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dissolution behavior of hydroxyapatite microspheres in HBSS2014

    • Author(s)
      Zhang Zhongying, Isao Kimura
    • Organizer
      化学工学会新潟大会
    • Place of Presentation
      新潟大学(新潟県)
    • Year and Date
      2014-11-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] リン酸カルシウム系化合物の生成に及ぼす疑似体液の流動乱れの影響2014

    • Author(s)
      佐藤裕昭, 田口佳成, 木村勇雄
    • Organizer
      日本セラミックス協会東北北海道支部研究発表会
    • Place of Presentation
      秋田市にぎわい交流館AU(秋田県)
    • Year and Date
      2014-11-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] Solubility of hydroxyapatite microspheres synthesized in a W/O/W emulsion2014

    • Author(s)
      Zhang Zhongying, Isao Kimura
    • Organizer
      日本化学会北海道支部2014年夏季研究発表会
    • Place of Presentation
      苫小牧高専(北海道)
    • Year and Date
      2014-07-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Deposition of calcium phosphate on titanium in a confined space

    • Author(s)
      Isao Kimura, Hiroaki Sato, Yoshinari Taguchi
    • Organizer
      Collaborative Conference on 3D & Materials Research 2013
    • Place of Presentation
      Jeju(韓国)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 制限空間内でのリン酸カルシウム系化合物の生成に及ぼす混合特性の影響

    • Author(s)
      佐藤裕昭, 田口佳成, 木村勇雄
    • Organizer
      化学工学会第45回秋季大会
    • Place of Presentation
      岡山大学(岡山県)
    • Related Report
      2013 Research-status Report
  • [Presentation] 疑似体液からの化合物生成装置の作製と混合特性評価

    • Author(s)
      佐藤裕昭, 田口佳成, 木村勇雄
    • Organizer
      化学工学会第78年会
    • Place of Presentation
      大阪大学(大阪府)
    • Related Report
      2012 Research-status Report
  • [Presentation] 制限空間内でのヒドロキシアパタイトの生成に及ぼす疑似体液間欠流通の影響

    • Author(s)
      佐藤裕昭, 田口佳成, 木村勇雄
    • Organizer
      日本セラミックス協会2013年年会
    • Place of Presentation
      東京工業大学(東京都)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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