• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Novel surface treatment process for forming thin hydroxyapatite coating on titanium

Research Project

Project/Area Number 24560841
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Structural/Functional materials
Research InstitutionKitami Institute of Technology

Principal Investigator

OHTSU Naofumi  北見工業大学, 工学部, 准教授 (10400409)

Research Collaborator ARAI Hirofumi  
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsチタンインプラント / ハイドロキシアパタイト被膜 / 骨親和性 / 熱化学処理 / 細胞培養試験 / 医療用インプラント材料 / 表面処理 / チタン / 金属生体材料 / 硬組織適合性 / アパタイト皮膜 / リン酸カルシウム析出 / 皮膜密着強度
Outline of Final Research Achievements

We developed a novel and simple surface treatment process for forming thin hydroxyapatite coating of nanometer thickness on titanium. In the present research, optimization of the treatment parameters was performed, and thereafter, biocompatibility of the treated titanium was evaluated, in order to complete this process. The coating using optimum condition consisted of hydroxyapatite with excellent bonding strength, and its thickness was ca. 300 nm. Furthermore, the cell tests demonstrated that the treated-titanium has sufficient biosafety similar to an untreated surface and can activate a bone-formation of osteoblast.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (17 results)

All 2015 2014 2013 2012

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Acknowledgement Compliant: 2 results) Presentation (11 results) Book (1 results)

  • [Journal Article] Response of osteoblast-like MC3T3-E1 cells on bioactive titanium fabricated by a chemical treatment process using a calcium-phosphate slurry2014

    • Author(s)
      N. Ohtsu, M. Hirano, H. Arai
    • Journal Title

      Journal of Biomedical Materials Research Part A

      Volume: 102 Issue: 11 Pages: 3838-3845

    • DOI

      10.1002/jbm.a.35053

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effect of sterilization and water rinsing on cell adhesion to titanium surfaces2014

    • Author(s)
      M. Hirano, T. Kozuka, Y. Asano, Y. Kakuchi, H. Arai, N. Ohtsu
    • Journal Title

      Applied Surface Science

      Volume: 311 Pages: 498-502

    • DOI

      10.1016/j.apsusc.2014.05.096

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effect of treatment temperature on the biocompatibility and mechanical strength of hydroxyapatite coating formed on titanium using calcium phosphate slurry2014

    • Author(s)
      N. Ohtsu, T. Takahara, M. Hirano, H. Arai
    • Journal Title

      Surface and Coatings Technology

      Volume: 239 Pages: 185-190

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Selectable surface nitridation of titanium using focused pulsed Nd:YAG laser irradiation with nitrogen gas blow2014

    • Author(s)
      N. Ohtsu, W. Saito, M. Yamane
    • Journal Title

      Surface and Coatings Technology

      Volume: 246 Pages: 52-56

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Thickness of titanium nitride layers formed by focused low-power pulsed Nd:YAG laser irradiation in nitrogen atmospheres2014

    • Author(s)
      N. Ohtsu, W. Saito, M. Yamane
    • Journal Title

      Surface and Coatings Technology

      Volume: 244 Pages: 57-62

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] スラリー埋没加熱処理を用いたAgを含むアパタイト複合酸化物皮膜の抗菌持続性2015

    • Author(s)
      角地優子、平野満大、小俣雅嗣、大津直史
    • Organizer
      日本金属学会2015年春季大会
    • Place of Presentation
      東京大学駒場キャンパス
    • Year and Date
      2015-03-18 – 2015-03-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Effects of electrolyte on surface chemistry and cellular response of anodized titanium2014

    • Author(s)
      N. Ohtsu, T. Kozuka, H. Arai
    • Organizer
      7th Vacuum and Surface Science Conference on Asia and Australia (VASSCAA-7)
    • Place of Presentation
      新竹/(台湾)
    • Year and Date
      2014-10-05 – 2014-10-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Characteristic and cellular response on titanium surface treated by nitrogen/oxygen mixed gas plasma2014

    • Author(s)
      M. Hirano, M. Yamane, N. Ohtsu
    • Organizer
      7th Vacuum and Surface Science Conference on Asia and Australia (VASSCAA-7)
    • Place of Presentation
      新竹/(台湾)
    • Year and Date
      2014-10-05 – 2014-10-09
    • Related Report
      2014 Annual Research Report
  • [Presentation] Surface modification of titanium using laser induced nitrogen plasma2014

    • Author(s)
      N. Ohtsu, W. Saito, M. Yamane
    • Organizer
      15th International Conference on Plasma Surface Engineering
    • Place of Presentation
      ガルミッシュパルテンキルヘン(ドイツ)
    • Year and Date
      2014-09-15 – 2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] スラリー埋没加熱処理を用いた銀/アパタイト複合酸化皮膜の作製2014

    • Author(s)
      高原豊文、浅野勇太、小俣雅嗣、大津直史
    • Organizer
      日本金属学会
    • Place of Presentation
      東京工業大学
    • Related Report
      2013 Research-status Report
  • [Presentation] スラリー埋没加熱処理Ag/アパタイト複合酸化物被膜の細胞適合性および抗菌性能2014

    • Author(s)
      大津直史、浅野勇太、高原豊文
    • Organizer
      日本金属学会
    • Place of Presentation
      東京工業大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 酸素プラズマ処理したチタン材料の細胞適合性評価2013

    • Author(s)
      平野満大、斉藤渉、小塚太朗、浅野勇太、大津直文
    • Organizer
      日本金属学会
    • Place of Presentation
      金沢大学
    • Related Report
      2013 Research-status Report
  • [Presentation] レーザー照射を利用した選択的チタン表面窒化処理2013

    • Author(s)
      斉藤渉、山根美佐雄、大津直史
    • Organizer
      日本金属学会
    • Place of Presentation
      金沢大学
    • Related Report
      2013 Research-status Report
  • [Presentation] スラリー埋没加熱処理アパタイト皮膜チタン材料上での細胞活性評価2013

    • Author(s)
      平野満大、久慈泰介、新井博文、大津直史
    • Organizer
      日本金属学会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
  • [Presentation] スラリー埋没加熱処理アパタイト被覆チタン材料の in vitro 評価2012

    • Author(s)
      大津直史、平野満大、新井博文
    • Organizer
      日本金属学会
    • Place of Presentation
      松山
    • Related Report
      2012 Research-status Report
  • [Presentation] スラリー埋没加熱処理における熱処理温度が皮膜密着強度および細胞接着に与える影響2012

    • Author(s)
      高原豊文、平野満大、大津直史
    • Organizer
      日本金属学会
    • Place of Presentation
      松山
    • Related Report
      2012 Research-status Report
  • [Book] バイオマテリアル研究の最前線2014

    • Author(s)
      大津直史
    • Total Pages
      2
    • Publisher
      スラリーを利用したチタン表面へのHApコーティング -新しいウエットプロセスによる生体機能性薄膜の形成―
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi