Control of the internal and surface structures of biodegradable porous membranes with the aid of surfactants and their application to bioprocess
| Project/Area Number |
24560957
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
KAWASE Tomoyuki 新潟大学, 医歯学系, 准教授 (90191999)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 多孔質膜 / 生分解性材料 / 生体材料 / バイオプロセス / バイオセパレーション / 国際情報交換 / アメリカ合衆国 |
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| Outline of Final Research Achievements |
Biodegradable separation membrane and scaffold materials have been developed by controlling their internal and surface structures with the aid of surfactants. Asymmetric microporous separation membranes of poly(L-lactic acid) with pores in the order of 0.1 μm were prepared from the polymer solutions containing surfactants with the hydrophilic-lipophilic balance (HLB) values from 15.3 to 16.7. Osteoblast-like cells grew in the 500 μm-thick biodegradable microporous membranes when the cells were seeded on the rough side of the membranes.
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Report
(5 results)
Research Products
(21 results)
