| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
Histone deacetylase6 (HDA6) is a chromatin modifier to establish the heterochromatin structure in Arabidopsis thaliana. We identified working points and target genes of HDA6 complex on the Arabidopsis genome. HDA6 specifically binds to genes responded to jasmonic acid signaling network required for the water deficit responses and COPIA type retro-transporsable element in heterochromatin regions. From these results, it is suggested that there are at least two types of HDA6 complexes. First one is for gene regulation on euchromatic region, and second one is for silencing of heterochromatic region. Perhaps these two types of HDA6 complexes have division of labor on Arabidopsis genome. These results that single epigenetic factor functions different structural targets (euchromatin and heterochromatin) on plant genome are significant achievement to expand and to develop the research field of epigenetic study in plant science.
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