| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Outline of Final Research Achievements |
The paraventricular organ is one of the circumventricular organs in the diencephalon. In this study, there was paraventricular organ in the brain of clawed frog (Amphibia), redspotted masu trout (Teleostei) and lamprey (Cyclostomata). Their paraventricular organ formed the neural connection to the pituitary gland through the GnIH (gonadotropin-inhibitory hormone) neurons and/or the GnRH (gonadotropin-releasing hormone) neurons. In addition, the serotonin-immunoreactive cells which were similar to the cerebrospinal fluid contacting neurons of the vertebrate were found around the frontal eye in the amphioxus. These suggest that the chordate except mammals possess the paraventricular organ, which make a neural network with the pituitary gland. However, the function of the paraventricular organ is still unknown.
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