Genetic basis of adaptive population divergence in androgen signaling for a fish in relation to mating system
| Project/Area Number |
24570105
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biodiversity/Systematics
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| Research Institution | Fukui Prefectural University |
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Principal Investigator |
KOKITA Tomoyuki 福井県立大学, 海洋生物資源学部, 准教授 (60372835)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 生態ゲノミクス / 行動生態学 / 繁殖システム / 繁殖戦略 / 適応進化 / 雄性ホルモン / 自然選択 / 魚類 / 行動生態 / 行動遺伝 / 行動ゲノミクス / 原因DNA変異 / 行動遺伝学 / 性ホルモン / エコゲノミクス / QTLマッピング / トランスクリプトミクス / 性ステロイド |
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| Outline of Final Research Achievements |
Extreme diversity in male reproductive strategy is found in fishes. Elucidating genetic basis of such diversity is important for understanding its evolutionary mechanism. Androgen is a key hormone for the expression of multiple male reproductive traits that are important for male reproductive success. Therefore, selection on androgen-mediated traits might result in the adaptive evolution of androgen titers themselves. We used natural variation in androgen-mediated traits and androgen production between different ecotype populations of the Japanese freshwater threespined stickleback as a model system. Ecological genomic analyses including comparative transcriptome and QTL mapping and a variety of molecular biology experiments were conducted to examine this prediction. This study suggests that adaptive divergence in androgen production between these populations occurred by regulatory mutations of a gene that encodes an important enzyme for androgen synthesis.
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Report
(4 results)
Research Products
(19 results)
