Study of Dynamic Structures of Protein molecules by single molecule force spectroscopy
| Project/Area Number |
24570128
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Structural biochemistry
|
|---|
| Research Institution | Yamagata University (2014)
Japan Advanced Institute of Science and Technology (2012-2013) |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | タンパク質 / 原子間力顕微鏡 / 一分子計測 / ポリペプチド / １分子測定 / 粘弾性 / 天然変性タンパク質 |
|---|
| Outline of Final Research Achievements |
We Studied the dynamic structures of various polypeptides at single molecule level using the technique of Atomic force microscopy. Single molecule force spectroscopy reveaed that Polyglutamic acid, polylysine have very flexible structure, while polyproline has a very rigid, resilient structure.
|
Report
(4 results)
Research Products
(8 results)
