| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
We have more than several thousands of whole genome sequences of many divergent species, but more than half of the genes on the genomes are still uncharacterized. It is almost impossible to determine all functions of all genes by experimental procedure, and thus some computational approaches to infer some possible functions of the uncharacterized genes. In this study, we have constructed integrated networks by using RNA-seq based co-expression networks and high throughput protein-protein interaction data, and developed a method to compare the integrated networks among the species. We also developed a new clustering method and applied it to infer the cellular function of uncharacterized genes.
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