Functional analysis of cell cycle-associated microRNAs
| Project/Area Number |
24570201
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Molecular biology
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| Research Institution | Meiji University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | マイクロＲＮＡ / エピジェネティクス |
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| Outline of Final Research Achievements |
MicroRNA (miRNA) has been shown to be involved in regulation of the etiology of serious illness such as cancer and metabolic diseases. It is estimated that human cells have approximately more than 1,000 kinds of miRNAs. In this study, we focused on five miRNAs that could be associated with cell cycle regulation and aimed to reveal functional aspects including target gene identification and epigenetic regulation of miRNAs. It is expected that the results obtained from this study would be useful not only for diagnosis of cancer but also for epigenetic therapy and for promotion of microRNA-based medicine.
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Report
(4 results)
Research Products
(4 results)
