Genome wide search for target genes of Drosophila histone methyl transferase dG9a

• Project/Area Number: 24570211
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cell biology
• Research Institution: Kyoto Institute of Technology
• Principal Investigator: YAMAGUCHI Masamitsu 京都工芸繊維大学, 工芸科学研究科, 教授 (00182460)
• Co-Investigator(Kenkyū-buntansha): YOSHIDA Hideki 京都工芸繊維大学, 大学院工芸科学研究科, 助教 (30570600)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000); Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 発生・分化 / 遺伝学 / 昆虫 / ヒストンメチル化酵素 / EGFR経路 / 形態形成 / オートファジー / RNA-seq / 遺伝子 / エピゲノム

Outline of Final Research Achievements

We have identified segmentation genes that are upregulated in embryos of Drosophila G9a (dG9a) mutant. Since temporal and spatial expression pattern of these segmentation genes are not changed in dG9a mutant embryos in compared with the wild type, delay in embryogenesis of the dG9a mutant is likely caused by the changes in expression level of their mRNAs. Genome wide genetic screen by using the rough eye phenotype induced by eye disc specific dG9a-overexpression identified a set of genes involved in the EGFR signaling pathway and autophagy. In consistent with these observations, the dG9a mutant showed high sensitivity to starvation stress that induce autophagy. These findings provide important clues to clarify epigenetic regulation of autophagy.

Research Products

• [Journal Article] Drosophila myeloid leukemia factor acts with DREF to activate the JNK signaling pathway. (2014)
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  • Journal Title: Oncogenesis Volume: 3 Issue: 4 Pages: 1-7
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  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] DNA polymerase alpha interacts with PrSet7 and mediates H4K20 monomethylation in Drosophila. (2014)
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• [Journal Article] Metabolome analysis of Drosophila melanogaster during embryogenesis. (2014)
  • Author(s): Thuy An, P. N., Yamaguchi, M., Bamba, T. and Fukusaki, E.
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• [Journal Article] Genetic link between Cabeza, a Drosophila homologue of Fused in Sarcoma (FUS), and the EGFR signaling pathway (2014)
  • Author(s): Shimamura M, Nakagawa M, Yamaguchi M et al.
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• [Journal Article] Role of SCOX in determination of Drosophila melanogaster lifespan. (2014)
  • Author(s): Nguyen, T. B., Ida, H., Shimamura, M., Kitazawa, D., Akao, S., Yoshida, H., Inoue, Y. H. and Yamaguchi, M.
  • Journal Title: American J. Cancer Res. Volume: 4(4) Pages: 325-336
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• [Journal Article] Structural characterization and subcellular localization of Drosophila organic solute carrier partner 1. (2014)
  • Author(s): Tho Huu, N, Yoshida, Umegawachi, T, Miyata, S, Yamaguchi, M
  • Journal Title: BMC Biochemistry Volume: 15 Issue: 1 Pages: 11-11
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  • Peer Reviewed / Open Access
• [Journal Article] Drosophila DOCK family protein Sponge regulates the JNK pathway during thorax development. (2014)
  • Author(s): Morishita, K., Ozasa, F., Eguchi, K., Yoshioka, Y., Yoshida, H., Hiai, H. and Yamaguchi, M.
  • Journal Title: Cell Struct. Funct. Volume: 39 Pages: 113-124
  • NAID: 130004693783
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The Hippo pathway as a target of the Drosophila DRE/DREF transcriptional regulatory pathway. (2014)
  • Author(s): Vo, N., Horii, T., Yanai, H., Yoshida, H. and Yamaguchi, M.
  • Journal Title: Sci. Rep. Volume: 4 Issue: 1 Pages: 7196-7196
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• [Journal Article] Ubiquitin carboxyl hydrolase L1 significance for human diseases. (2014)
  • Author(s): Suong, D. N. A., Thao, D. T. P., Yamaguchi, M. and Thuoc, T. L.
  • Journal Title: Protein Peptide Lett. Volume: 21(7) Issue: 7 Pages: 624-630
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  • Peer Reviewed / Open Access
• [Journal Article] Drosophila MCM10 is required for DNA replication and differentiation in the compound eye. (2014)
  • Author(s): Vo, N., Taga, A., Inaba, Y., Hideki, Y., Cotterill, S. and Yamaguchi, M.
  • Journal Title: PLoS ONE Volume: 9 Issue: 3 Pages: 1-15
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• [Journal Article] Identification of ter94, Drosophila VCP, as a strong modulator of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS (2014)
  • Author(s): Azuma Y., Tokuda T., Shimamura M., Kyotani A., Sasayama H., Yoshida T., Mizuta I., Mizuno T., Nakagawa M., Fujikake N., Ueyama M., Nagai Y., Yamaguchi M
  • Journal Title: Hum. Mol. Genet Volume: 23(13) Issue: 13 Pages: 3467-3480
  • DOI: 10.1093/hmg/ddu055
  • Peer Reviewed
• [Journal Article] DNA polymerase alpha interacts with PrSet7 and mediates H4K20 monomethylation in Drosophila. (2014)
  • Author(s): Sahashi, R., Crevel G., Pasko, J., Suyari, O., Nagai, R., Saura, M. M., Yamaguchi, M. and Cotterill, S.
  • Journal Title: J. Cell Science Volume: 未定
  • Peer Reviewed
• [Journal Article] dNF-YB plays dual roles in cell death and cell differentiation during Drosophila eye development. (2013)
  • Author(s): Ly, L. L., Suyari, O., Yoshioka, Y., Tue, N. T., Yoshida, H., Yamaguchi, M.
  • Journal Title: Gene Volume: 520 Issue: 2 Pages: 106-118
  • DOI: 10.1016/j.gene.2013.02.036
  • Peer Reviewed
• [Journal Article] Overexpression of Drosophila RFX3 induces apoptosis and interferes with differentiation of photoreceptor cells. (2013)
  • Author(s): Sugimoto, T., Ueda, T., Yoshida, H., Murakami, A. and Yamaguchi, M.
  • Journal Title: J. Carcinogene. Mutagene. Volume: 4(1) Issue: 02 Pages: 1-7
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• [Journal Article] The Drosophila DOCK family protein Sponge is involved in differentiation of R7 photoreceptor cells. (2013)
  • Author(s): Eguchi, K., Yoshioka, Y., Yoshida, H., Morishita, K., Miyata, S., Hiai, H. and Yamaguchi, M.
  • Journal Title: Exp. Cell Res. Volume: 315 (14) Issue: 14 Pages: 2179-2195
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  • Peer Reviewed
• [Journal Article] Temporal and spatial pattern of dref expression during Drosophila bristle development. (2013)
  • Author(s): Kawamori, A., Shimaji, K. and Yamaguchi, M.
  • Journal Title: Cell Struct. Funct. Volume: 38 Pages: 169-181
  • NAID: 130004137594
  • Peer Reviewed
• [Journal Article] Control of e2f1 and PCNA by Drosophila transcription factor DREF. (2013)
  • Author(s): Kawamori, A., Shimaji, K. and Yamaguchi, M.
  • Journal Title: Genesis Volume: 51 Issue: 11 Pages: 741-750
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  • Peer Reviewed
• [Journal Article] Genetic link between Heme Oxygenase and the signaling pathway of DNA damage in Drosophila melanogaster. (2013)
  • Author(s): Ida, H., Suyari, O., Shimamura, M., Tran, T. T., Yamaguchi, M. and Taketani, S.
  • Journal Title: Tohoku J. Exp. Med. Volume: 231 Pages: 117-125
  • NAID: 130004822383
  • Peer Reviewed
• [Journal Article] Functional analysis of Drosophila DNA polymerase ε p58 subunit. (2013)
  • Author(s): Sahashi, R., Matsuda, R., Suyari, O., Kawai, M., Yoshida, H., Cotterill, S. and Yamaguchi, M.
  • Journal Title: Am. J. Cancer Res. Volume: 3(5) Pages: 478-489
  • Peer Reviewed
• [Journal Article] DREF, a concertmaster for Hippo pathway and JNK pathway in Drosophila. (2013)
  • Author(s): Fujiwara, S., Yoshida, H. and Yamaguchi, M.
  • Journal Title: J. Carcinogene. Mutagene. Volume: 4 Issue: 02
  • DOI: 10.4172/2157-2518.1000e110
  • Peer Reviewed
• [Journal Article] Nuclear transcription factor Y and its roles in cellular processes related to human disease. (2013)
  • Author(s): Ly, L.L., Yoshida, H. and Yamaguchi, M.
  • Journal Title: Am. J. Cancer Res. Volume: 3(4) Pages: 339-346
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• [Journal Article] Dynamics of endoreplication during Drosophila posterior scutellar macrochaete development. (2012)
  • Author(s): Kawamori, A., Shimaji, K. and Yamaguchi, M.
  • Journal Title: PLoS ONE Volume: 7(6), Issue: 6 Pages: e38714-e38714
  • DOI: 10.1371/journal.pone.0038714
  • Peer Reviewed
• [Journal Article] COPI-mediated membrane trafficking is required for cytokinesis in Drosophila male meiotic divisions (2012)
  • Author(s): Kitazawa D, Yamaguchi M, Mori. H, Inoue YH
  • Journal Title: J. Cell Sci Volume: 125 Issue: 15 Pages: 3649-60
  • DOI: 10.1242/jcs.103317
  • Peer Reviewed
• [Journal Article] Knockdown of the Drosophila Fused in Sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches. (2012)
  • Author(s): Sasayama, H., Shimamura, M., Tokuda, T., Azuma, Y., Yoshida, T., Mizuno, T., Nakagawa, M., Fujikake, N., Nagai, Y. and Yamaguchi, M
  • Journal Title: PLoS ONE Volume: 7(6), Issue: 6 Pages: e39483-e39483
  • DOI: 10.1371/journal.pone.0039483
  • Peer Reviewed
• [Journal Article] Sarcoglycan complex formation is involved in regulation of EGFR signaling during Drosophila eye development. (2012)
  • Author(s): Hashimoto, R., Yoshida, H. and Yamaguchi, M.
  • Journal Title: HOAJ Biology, Volume: 1(1) Issue: 1 Pages: 1-1
  • DOI: 10.7243/2050-0874-1-7
  • Peer Reviewed
• [Journal Article] The warts gene as a novel target of the Drosophila DRE/DREF transcription pathway. (2012)
  • Author(s): Fujiwara, S., Ida, H., Yoshioka, Y., Yoshida, H. and Yamaguchi, M.
  • Journal Title: Am. J. Cancer Res. Volume: 2 Pages: 36-44
  • Peer Reviewed
• [Journal Article] Differential requirement for the N-terminal catalytic domain of the DNA polymerase ε p255 subunit in the mitotic cell cycle and the endocycle. (2012)
  • Author(s): Suyari, O., Kawai, M., Ida, H., Yoshida, H., Sakaguchi, K. and Yamaguchi, M.
  • Journal Title: Gene Volume: 495 (2), Issue: 2 Pages: 104-114
  • DOI: 10.1016/j.gene.2011.12.056
  • Peer Reviewed
• [Journal Article] Roles of histone H3K9 methyltransferases during Drosophila spermatogenesis (2012)
  • Author(s): Ushijima Y, Inoue YH, Konishi T, Kitazawa D, Yoshida H, Shimaji K, Kimura H, Yamaguchi M
  • Journal Title: Chromosome Research Volume: 3 Issue: 3 Pages: 319-31
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• [Journal Article] RNA-based diagnosis in a multicellular specimen by whole mount in situ hybridization using an RNA-specific probe. (2012)
  • Author(s): Ueda T., Kobori, A., Yamayoshi, A., Yoshida, H., Yamaguchi, M. , Murakami, A.
  • Journal Title: Bioorganic & Medicinal Chemistry Volume: 20 Issue: 20 Pages: 6034-6039
  • DOI: 10.1016/j.bmc.2012.08.028
  • Peer Reviewed
• [Presentation] Drosophila Mcm10 is required for DNA replication and differentiation in the compound eye: possible interaction with HP4 and HP6 (2014)
  • Author(s): The Thi Thanh Vo, Sue Cotterill, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] ALSモデルショウジョウバエを用いた分子シャペロンdmrjの生体内機能解析 (2014)
  • Author(s): 山本格、東裕美子、京谷茜、吉田英樹、水田依久子、上山盛夫、藤掛伸宏、水野敏樹、徳田隆彦、山口政光
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] 筋萎縮性側索硬化症(ALS)の分子病態解明へ向けての原因遺伝子FIG4を用いたショウジョウバエモデルの構築 (2014)
  • Author(s): 京谷茜、東裕美子、吉田英樹、水田依久子、水野敏樹、徳田隆彦、山口政光
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Role of histone methyltransferases dG9a during Drosophila embryogenesis – genome-wide identification of target genes (2014)
  • Author(s): Kohei Shimaji, Takahiro Konishi, Shintaro Tanaka, Hideki Yoshida, Yasuko Kato, Yasuyuki Ohkawa, Tetsuya Sato, Mikita Suyamam Hiroshi Kimura, Masamitsu Yamaguchi
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] ショウジョウバエDOCK-familyタンパク質Ziziminの生体内機能解析 (2014)
  • Author(s): 小笹史登、森下和茂、宮嶋久雄、吉田英樹、宮田清司、山口政光
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] ショウジョウバエエピジェネティックス制御因子Jumonji(dJmj)/Jarid2の核小体への局在 (2014)
  • Author(s): 後藤萌、戸田成美、吉田英樹、井上喜博、木村宏、山口政光
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] ショウジョウバエ転写因子DREFによるHippo経路制御機構の解明 (2014)
  • Author(s): 堀井健志、Vo Nicole、梁井啓史、吉田英樹、山口政光
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] ショウジョウバエ転写因子DREFとその相互作用因子群との相互作用の可視化 (2014)
  • Author(s): 吉野那月、The Thi Thanh Vo、廣瀬富美子、Mario Zurita、吉田英樹、山口政光
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] yki mRNAの細胞内局在を制御するシス配列とトランス因子の同定 (2014)
  • Author(s): 田中祐、梅河内隆成、山口政光、吉田英樹
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] A genome-wide screen for mRNAs targeting the ER in SRP-independent manner, and analysis on subcellular localization of yki mRNA (2014)
  • Author(s): Takanari Umegawachi, Hiromu Koshida, Momoko Yamada, Kazuma Usui, Tesuya Sato, Mikita Suyama, Megumi Ito, Yasuyuki Ohkawa, Masamitsu Yamaguchi, Hideki Yoshida
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Overexpression of tumor suppressor protein OSCP1/NOR1 induces apoptosis, ROS generation and ER stress during development of Drosophila melanogaster (2014)
  • Author(s): Tho Nguyen Huu, Yoshida Hideki, Yamaguchi Masamitsu
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] ショウジョウバエ初期胚で見られるスプライシングバリアントによる細胞内局在の違い (2014)
  • Author(s): 西野冴香、田中領、Henry Krause、山口政光、吉田英樹
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] ショウジョウバエ初期胚を用いたpseudo-cleavage furrow局在を示すmRNAの局在化機構の解析 (2014)
  • Author(s): 田中領、西野冴香、Henry Krause、山口政光、吉田英樹
  • Organizer: 第37回 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜（横浜市）
  • Year and Date: 2014-11-25 – 2014-11-27
• [Presentation] Multiple reles of Drosophila Mcm10 during compound eye development (2014)
  • Author(s): Nicole Vo, Hideki Yoshida, Sue Cotterill, Masamitsu Yamaguchi
  • Organizer: 第66回日本細胞生物学会大会
  • Place of Presentation: 奈良県新公会堂（奈良市）
  • Year and Date: 2014-06-11 – 2014-06-13
• [Presentation] Drosophila Mcm10 is required for DNA replication and differentiation in the compound eye (2014)
  • Author(s): Thi Thanh The Vo, Hideki Yoshida, Sue Cotterill, Masamitsu Yamaguchi
  • Organizer: The 11th Japanese Drosophila Research Conference
  • Place of Presentation: 金沢歌劇座（金沢市）
  • Year and Date: 2014-06-04 – 2014-06-06
• [Presentation] Functional analysis of Drosophila histone methyltransferase G9a (2014)
  • Author(s): Kohei Shimaji, Shintaro Tanaka, Hiroshi Kimura, Yasuyuki Ohkawa, Tetsuya Sato, Mikita Suyama, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: The 11th Japanese Drosophila Research Conference
  • Place of Presentation: 金沢歌劇座（金沢市）
  • Year and Date: 2014-06-04 – 2014-06-06
• [Presentation] Localization analysis of predicted pseudo cleavage furrow-localized mRNA in Drosophila early embryos (2014)
  • Author(s): Ryo Tanaka, Saeka Nishino, Henry Krause, Masamitsu Yamaguchi, Hideki Yoshida
  • Organizer: The Nineteenth Annual Meeting of the RNA Society
  • Place of Presentation: Quebec city convention centre（カナダ・ケベックシティ）
  • Year and Date: 2014-06-03 – 2014-06-08
• [Presentation] Identification of non-canonical mRNAs targeting to the ER and analysis on subcellular localization of mRNAs by RNA imaging system (2014)
  • Author(s): Takanari Umegawachi, Hiromu Koshida, Momoko Yamada, Kazuma Usui, Tesuya Sato, Mikita Suyama, Megumi Ito, Yasuyuki Ohkawa, Masamitsu Yamaguchi, Henry M. Krause, Hideki Yoshida
  • Organizer: The Nineteenth Annual Meeting of the RNA Society
  • Place of Presentation: Quebec city convention centre（カナダ・ケベックシティ）
  • Year and Date: 2014-06-03 – 2014-06-08
• [Presentation] ショウジョウバエ骨髄性白血病因子dMLFは転写因子DレFのコファクターとして働きJNK遺伝子を転写活性化する。 (2013)
  • Author(s): 梁井啓史、吉岡泰秀、吉田英樹、山口政光
  • Organizer: 第65回日本細胞生物学会大会
  • Place of Presentation: ウインクあいち（名古屋）
• [Presentation] 非古典的経路で小胞体へ標的化するmRNAの同定及び同機構解析系の構築 (2013)
  • Author(s): 梅河内隆成、越田大夢、山田百子、臼井一馬、佐藤哲也、須山幹太、伊藤恵美、大川恭行、山口政光、吉田英樹
  • Organizer: 第65回日本細胞生物学会大会
  • Place of Presentation: ウインクあいち（名古屋）
• [Presentation] DNA複製制御におけるショウジョウバエDNAポリメラーゼαとヒストンメチル化酵素Pr-Set7との相互作用 (2013)
  • Author(s): 佐橋律子、須鎗理、Giles Crevel、 Sue Cotterill、山口政光
  • Organizer: 第65回日本細胞生物学会大会
  • Place of Presentation: ウインクあいち（名古屋）
• [Presentation] Multiple roles of Drosophila Mcm10 during compound eye development (2013)
  • Author(s): Nicole Vo, Taga Ayano, Yasuhiro Inaba, Hideki Yoshida, Sue Cotterill, Masamitsu Yamaguchi
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸ポートピアアイランド
• [Presentation] Dynamics of epigenetic regulator jumonji (Jarid2) during Drosophila spermatogenesis (2013)
  • Author(s): Narumi Toda, Nobuhiro Sasai, Hideki Yoshida, Yoshihiro Inoue, Hiroshi Kimura, Masamitsu Yamaguchi
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸ポートピアアイランド
• [Presentation] A Drosophila model for functional analysis of Organic Carrier partner 1 (2013)
  • Author(s): Nguyen Tho Huu, Seiji Miyata, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸ポートピアアイランド
• [Presentation] Cabeza that has been identified in Amyotrophic Lateral Sclerosis regulates the EGFR signaling pathway in Drosophila (2013)
  • Author(s): Akane Kyotani, Mai Shimamura, Yumiko Azuma, Takahiko Tokuda, Ikuko Mizuta, Masanari Nakagawa, Toshiki Mizuno, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸ポートピアアイランド
• [Presentation] Drosophila transcription factor DREF genetically interacts with tumor suppressor genes (2013)
  • Author(s): Yukari Terakata, Takeshi Horii, Shunsuke Fujiwara, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸ポートピアアイランド
• [Presentation] Functional analysis of Drosophila DOCK-family Zizimin (2013)
  • Author(s): Fumito Ozasa, Kazushige Morishita, Hideki Yoshida, Seiji Miyata, Masamitsu Yamaguchi
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸ポートピアアイランド
• [Presentation] ショウジョウバエDNAポリメラーゼε p255サブユニットと相互作用する遺伝子の探索 (2012)
  • Author(s): 前田 頌太、須鑓 理、佐橋 律子、稲葉 泰裕、吉田 英樹、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡
• [Presentation] ショウジョウバエDOCK family遺伝子の機能解析 (2012)
  • Author(s): 森下 和茂、小笹 史登、吉田 英樹、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡
• [Presentation] A Drosophila Model for Function Analysis of Organic Carrier Partner 1 (2012)
  • Author(s): Nguyen Huu Tho, Masamitsu Yamaguchi, Hideki Yoshida, Seiji Miyata
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡
• [Presentation] ショウジョウバエ精子形成過程におけるエビジェネティック制御因子Jumonji(Jarid2)の動態 (2012)
  • Author(s): 戸田 成美、笹井 信広、吉田 英樹、井上 喜博、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡
• [Presentation] ショウジョウバエ転写因子DREFを中心とした転写制御ネットワーク : DREFの標的としてのHippo経路関連遺伝子の同定 (2012)
  • Author(s): 藤原 俊介、堀井 健志、平塚 賢、大川 恭行、須山 幹太、吉田 英樹、山口 政光
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡
• [Presentation] dNF-YB Plays Dual Roles in Cell Death and Cell Differentiation of Drosophila Eye Development (2012)
  • Author(s): Ly Luong Linh, Tue Nguyen Trong, Osamu Suyari, Yasuhide Yoshioka, Hideki Yoshida, Masamitsu Yamaguchi
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡
• [Presentation] mRNA新規小胞体標的化機構の分子メカニズムの解明 (2012)
  • Author(s): 梅河内隆成、臼井一馬、佐藤哲也、須山幹太、大川恭行、山口政光、吉田英樹
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡
• [Presentation] 蛍光タンパク質を基盤とした小胞他標的化RNA可視化システムの構築 (2012)
  • Author(s): 越田大夢、山田百子、梅河内隆成、Krause Henry、山口政光、吉田英樹
  • Organizer: 第35回日本分子生物学会年会
  • Place of Presentation: マリンメッセ福岡