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Study toward evolutionary formulation of vertebrate embryogenesis

Research Project

Project/Area Number 24570243
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Developmental biology
Research InstitutionThe University of Tokyo (2013-2014)
The Institute of Physical and Chemical Research (2012)

Principal Investigator

IRIE Naoki  東京大学, 理学(系)研究科(研究院), 准教授 (10536121)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords進化 / 発生学 / バイオインフォマティクス / 進化発生学 / 発生
Outline of Final Research Achievements

While vertebrates showed amazing morphological variations through evolution, they kept their basic anatomical features (or body plan) strictly conserved. The reason for this body plan conservation is still unclear. Our study tackled this problem by collecting and analyzing gene expression data for two frog species, and found that vertebrate body plan establishing stage is the stage of highest conservation. Although we could not clarify the exact mechanisms for the conservation, we have obtained inspiring hints to this problem.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (27 results)

All 2015 2014 2013 2012

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 5 results) Presentation (17 results) (of which Invited: 12 results) Book (4 results)

  • [Journal Article] Unexpected link between polyketide synthase and calcium carbonate biomineralization2015

    • Author(s)
      Motoki Hojo, Ai Omi, Gen Hamanaka, Kazutoshi Shindo, Atsuko Shimada, Mariko Kondo, Takanori Narita, Masato Kiyomoto, Yohei Katsuyama, Yasuo Ohnishi, Naoki Irie and Hiroyuki Takeda
    • Journal Title

      Zoological Letters

      Volume: 1 Issue: 1 Pages: 1-16

    • DOI

      10.1186/s40851-014-0001-0

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs.2014

    • Author(s)
      Richard E. et al.(著者55人中45番目)
    • Journal Title

      Science

      Volume: 12 Issue: 6215 Pages: 1254449-1254449

    • DOI

      10.1126/science.1254449

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The developmental hourglass model: a predictor of the basic body plan?2014

    • Author(s)
      Naoki Irie*, and Shigeru Kuratani
    • Journal Title

      Development

      Volume: 141 Issue: 24 Pages: 4649-4655

    • DOI

      10.1242/dev.107318

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evolutionary origin of vertebrate head: The problem of head segmentation in vertebrates.2014

    • Author(s)
      Onai, T., Irie, N., and Kuratani, S.
    • Journal Title

      Ann. Rev. Genom. & Human Genet.

      Volume: 15 Issue: 1 Pages: 443-459

    • DOI

      10.1146/annurev-genom-091212-153404

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Turtle ghrelin.2014

    • Author(s)
      Juan Pascual-Anaya, Amonida Zaddissa, Bronwen Aken, Guojie Zhang and Naoki Irie
    • Journal Title

      Nature Genetics

      Volume: 46 Issue: 6 Pages: 526-526

    • DOI

      10.1038/ng.2988

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan.2013

    • Author(s)
      Wang, Z., Pascual-Anaya, J., Zadissa, A., Li, W., Niimura, Y., Huang, Z., Li, C., White, S., Xiong, Z., Fang, D., et al.
    • Journal Title

      Nature genetics

      Volume: 45 Issue: 6 Pages: 701-706

    • DOI

      10.1038/ng.2615

    • Related Report
      2013 Research-status Report 2012 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] In search for more ancestral embryos2015

    • Author(s)
      Naoki Irie
    • Organizer
      CDB Symposium 2015
    • Place of Presentation
      理化学研究所 多細胞システム形成研究センター(兵庫県神戸市)
    • Year and Date
      2015-03-13 – 2015-03-15
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 動物進化と個体発生の統合的理解に向けて2014

    • Author(s)
      入江直樹
    • Organizer
      第37回 日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Easily changed early embryogenesis?2014

    • Author(s)
      Naoki Irie
    • Organizer
      X Meeting of the Spanish Society for Developmental Biology 2014
    • Place of Presentation
      マドリッド(スペイン)
    • Year and Date
      2014-10-13 – 2014-10-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 大規模トランスクリプトームから挑む進化発生学の古典問題2014

    • Author(s)
      入江直樹
    • Organizer
      日本遺伝学会 第86回大会
    • Place of Presentation
      長浜バイオ大学(滋賀県長浜市)
    • Year and Date
      2014-09-17 – 2014-09-19
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Remaining questions of the developmental hourglass model2014

    • Author(s)
      Naoki Irie
    • Organizer
      Euro EvoDevo 2014
    • Place of Presentation
      ウィーン(オーストリア)
    • Year and Date
      2014-07-22 – 2014-07-25
    • Related Report
      2014 Annual Research Report
  • [Presentation] Turtle also follows the general formulation of Embryonic Evolution.2013

    • Author(s)
      Naoki Irie
    • Organizer
      ICG-8
    • Place of Presentation
      ShenZhen, China
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Vertebrates' basic body plan embedded in the waist of hourglass. Bottleneck in evolution and development2013

    • Author(s)
      Naoki Irie
    • Organizer
      15th Annual meeting of the Society of Evolutionary Studies, Japan
    • Place of Presentation
      筑波 (茨城県)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Vertebrate phylotypic period as a source of basic body plan.2013

    • Author(s)
      Naoki Irie
    • Organizer
      International Society of Developmental Biology Conference 2013
    • Place of Presentation
      Cancun, Mexico
    • Related Report
      2013 Research-status Report
  • [Presentation] カメも従う動物発生進化の法則性?2013

    • Author(s)
      入江直樹
    • Organizer
      第36回 分子生物学会 Workshop 3AW14
    • Place of Presentation
      神戸 (兵庫県)
    • Related Report
      2013 Research-status Report
  • [Presentation] ネッタイツメガエル胚発生期の包括的遺伝子発現データ2013

    • Author(s)
      入江直樹
    • Organizer
      第84回 動物学会
    • Place of Presentation
      岡山 (岡山県)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 進化と発生の関係性をさぐるべく、de novo カメゲノム2013

    • Author(s)
      入江直樹
    • Organizer
      NGS現場の会 第3回大会
    • Place of Presentation
      神戸 (兵庫県)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] カメゲノムと脊椎動物ボディプラン2013

    • Author(s)
      入江直樹
    • Organizer
      第60回 日本実験動物学会総会
    • Place of Presentation
      筑波 (茨城県)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Turtle Genomes: Body Plan Evolution from Vertebrate Phylotype2013

    • Author(s)
      Naoki Irie
    • Organizer
      Plant and Animal Genome Conference Asia 2013
    • Place of Presentation
      Singapore, Grand Copthorn Hotel
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] What the Hourglass tells us about Vertebrate Development and Evolution2013

    • Author(s)
      Naoki Irie
    • Organizer
      CDB Symposium 2013
    • Place of Presentation
      神戸、理化学研究所
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Relationship between Ontogeny and Phylogeny of vertebrates.2013

    • Author(s)
      Naoki Irie
    • Organizer
      German-Japan Colloquium -Cellular Biochemistry Shaping Animals-
    • Place of Presentation
      Germany, KIT
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Re-formulating the Relationship Between Evolution and Development2012

    • Author(s)
      Naoki Irie
    • Organizer
      The 7th International Conference on Genomics & Bio-IT APAC 2012
    • Place of Presentation
      HongKong, Kawoloon Shangrila hotel
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Hopeful monster tackles the developmental hourglass model.2012

    • Author(s)
      Naoki Irie
    • Organizer
      Asia Pacific Developmental Biology Conference, EvoDevo satellite Meeting
    • Place of Presentation
      Taiwan, Taipei
    • Related Report
      2012 Research-status Report
    • Invited
  • [Book] 胚発生のロバストネスは進化にバイアスをかけているか?2014

    • Author(s)
      入江直樹
    • Total Pages
      5
    • Publisher
      細胞工学
    • Related Report
      2013 Research-status Report
  • [Book] 脊椎動物ファイロタイプとボディプラン進化2013

    • Author(s)
      入江直樹
    • Total Pages
      5
    • Publisher
      遺伝
    • Related Report
      2013 Research-status Report
  • [Book] 遺伝 2013年 3月号 「脊椎動物ファイロタイプとボディプラン進化」2013

    • Author(s)
      入江直樹、倉谷滋
    • Total Pages
      6
    • Publisher
      株式会社エヌ・ティー・エス
    • Related Report
      2012 Research-status Report
  • [Book] 物理科学月刊誌 パリティ 2013年1月号 特集:物理科学、この1年 「進化と発生の関係性定式化にみる生物のやわらかさ」2013

    • Author(s)
      入江直樹
    • Total Pages
      3
    • Publisher
      丸善出版
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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