Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Outline of Final Research Achievements |
In this study, we show that BslA was an amphiphilic protein that formed a repellent, protective layer on the surface of biofilms. We also show that B. subtilis responds to methyl salicylate, which is a plant signal that induces defense response in plants in response to infection of plant pathogens. In the presence of methyl salicylate, B. subtilis produced poly-gamma-glutamic acid and antibiotics. Poly-gamma-glutamic acid formed capsules, which protected cells against antimicrobials. These findings reveal the resistance mechanism of B. subtilis biofilms and plant-B. subtilis interaction.
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