Investigation of intracellular polyphosphate metabolism and its function in stress response in koji mold

• Project/Area Number: 24580132
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Applied microbiology
• Research Institution: National Agriculture and Food Research Organization
• Principal Investigator: KUSUMOTO Ken-Ichi 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・応用微生物研究領域, 上席研究員 (80353978)
• Co-Investigator(Renkei-kenkyūsha): SUZUKI Satoshi 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・応用微生物研究領域, 主任研究員 (90353979)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000); Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 麹菌 / ポリリン酸代謝

Outline of Final Research Achievements

Aspergillus oryzae is known as an important microorganism utilized as koji mold in fermentation food industry. In this study, the amount of polyphosphate was examined under several culture condition, and found that some effects were observed under the stress of metal ions, oxidation etc. Especially, polyphosphate was found to increase in response to some stress conditions. From these studies, new information concerning on polyphosphate was obtained, which was not known among filamentous fungi.

Research Products

• [Presentation] 麹菌Aspergillus oryzaeのポリリン酸代謝関連遺伝子の機能解析 (2014)
  • Author(s): 多田功生、大口ひかる、楠本憲一
  • Organizer: 第14回糸状菌分子生物学コンファレンス
  • Place of Presentation: 東北大学川内北キャンパス（宮城県仙台市）
  • Year and Date: 2014-11-16
• [Presentation] 麹菌Aspergillus oryzaeのポリリン酸代謝とストレス応答 (2013)
  • Author(s): 多田功生、大口ひかる、楠本憲一
  • Organizer: 第13回糸状菌分子生物学コンファレンス
  • Place of Presentation: 文部科学省研究交流センター（茨城県）