Elucidation of protection strategy for toxicity of D-amino acid in plant
| Project/Area Number |
24580151
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied biochemistry
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| Research Institution | Kansai University |
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Principal Investigator |
OIKAWA Tadao 関西大学, 化学生命工学部, 教授 (80233005)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | D-アミノ酸 / アミノ酸ラセマーゼ / シロイヌナズナ / D-セリン / L-セリン / セリンラセマーゼ |
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| Outline of Final Research Achievements |
We succeeded to construct the serine racemase gene-disruption mutant and overexpressed mutant of Arabidopsis thaliana. By using these mutants and wild-type strain of Arabidopsis thaliana, we evaluated the effects of various D- and L- amino acids on germination and growth of these strains. In case of D-serine, the serine racemase gene overexpressed mutant showed higher tolerant than other strains. This probably attributed to the D-serine degradation activity of serine rasemase. In case of L-serine, both serine racemase gene-disruption mutant and overexpressed mutant showed higher tolerant than wild-type strain.
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Report
(4 results)
Research Products
(6 results)
