| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Elucidation of biosynthetic mechanisms of structurally unique natural products makes it possible to understand the general principle of generation of structure diversity in natural products and utilize biosynthetic enzymes to create new natural products. Furthermore, it can provide useful information for the construction of potential compound library for drug discovery. In this study, we analyzed the biosynthetic origins and biosynthetic genes of several new secondary metabolites discovered in our laboratory from microorganisms and elucidated novel biosynthetic reactions involved in their synthesis.
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