| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Outline of Final Research Achievements |
The purpose of this study was to investigate the interactive effects of acetate and exercise training on lipid metabolism and endurance performance. Six-week-old SD rats were randomly assigned to four groups: water-injected (rest-water), acetate-injected (rest-ace), exercise-trained after injection of water (water-ex), and exercise-trained after injection of acetic acid (acetate-ex). Body weight in acetate-ex groups was significantly lower than that of water-injected group. Acetate-ex group showed an increase of exercise capacity and lipid oxidation during exercise tolerance test. Skeletal muscle of rats treated with acetic acid and exercise training led to higher expressions of cytochrome c (cycs), and tended to stimulate expressions of PGC1a and MHC1 genes than those of rest-water group. Those results indicate that treatments both of exercise training and intake of acetate contribute to enhancement of lipid metabolism and improvement of exercise capacity.
|
