• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Regulatory mechanisms for echinoderm muscle contraction

Research Project

Project/Area Number 24580293
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Fisheries chemistry
Research InstitutionHokkaido University

Principal Investigator

Tanaka Hiroyuki  北海道大学, 水産科学研究科(研究院), 助教 (90241372)

Research Collaborator HADANO Junji  
MORITA Takahiro  
NOTO Kouki  
ZUSHI Hideki  
HATTORI Kazuki  
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords棘皮動物 / 筋肉 / 筋収縮の調節 / トロポニン / ウニ / カルシウム / 筋収縮調節 / ミオシン / アクチン / トロポミオシン / ミオシンフィラメント / アクチンフィラメント
Outline of Final Research Achievements

Most of the musculature in echinoderms are smooth muscle and the contraction of which is believed to be regulated by the phosphorylation of myosin light chain depending on intracellular Ca2+ concentration as in the case of other smooth muscles in higher animals. In this study, troponin which is known as an actin-linked regulatory protein of striated muscles was revealed to be present in the various smooth muscles of sea urchin. The subunits of sea urchin troponin were obtained by the expression system constructed in Escherichia coli and were confirmed to be functional in vitro, even though they are lacking some regions which are known to be essential for the Ca2+-dependent activation of vertebrate striated muscle contraction. Therefore, the sea urchin troponin should activate the contraction by the acting mechanisms different from those of vertebrate troponin.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (1 results)

All 2015

All Presentation (1 results)

  • [Presentation] キタムラサキウニ平滑筋におけるトロポニンの存在2015

    • Author(s)
      波多野淳治・田中啓之
    • Organizer
      日本動物学会 第86回新潟大会
    • Place of Presentation
      朱鷺メッセ:新潟コンベンションセンター、新潟県、新潟市
    • Year and Date
      2015-09-17
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi