Study on research of regulation factor of unfertilized eggs in bivalves.

Research Project

Project/Area Number	24580296
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Fisheries chemistry
Research Institution	Tohoku Seikatsu Bunka Junior College (2013-2015) Tohoku University (2012)
Principal Investigator	Naganuma Takako 東北生活文化大学短期大学部, その他部局等, 准教授 (50250733)
Co-Investigator(Kenkyū-buntansha)	OGAWA TOMOHISA 東北大学, 大学院生命科学研究科, 准教授 (80240901) MURAMOTO KOUJI 東北大学, 大学院生命科学研究科, 教授 (90157800)
Project Period (FY)	2012-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000) Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords	レクチン / マベガイ / 生体防御 / カルシウム結晶化 / 生殖腺 / 二枚貝 / タンパク質 / 微生物 / LPS / 未成熟卵 / 生殖 / 卵母細胞
Outline of Final Research Achievements	The structures and physiological functions were studied on the several lectin fractions which purified from Pteria penguin pearl oyster. In these fractions, N-terminal sequences of five fractions were homologous reciprocally. These physiological functions were roughly classified into three groups. ① Self-defence function by agglutinating of gram negative bacteria and antigen presenting . ② Role as a matrix protein of calcium carbonate crystallization and as facilitating the aragonite crystal formation. ③ Involvement in the control of maturation in unfertilized eggs.