Effect of docosenoic acid and icosenoic acid on the type 2 diabetic mellitus and atopic dermatitis.
Project/Area Number |
24580305
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Fisheries chemistry
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Research Institution | Miyagi University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
TOMIOKA Yoshihisa 東北大学, 薬学研究科, 教授 (00282062)
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Project Period (FY) |
2012-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 脂質 / 水産利用学 / サンマ / ドコセン酸 / イコセン酸 / 2型糖尿病 / アトピー性皮膚炎 / 魚油 / 抗肥満 / 栄養機能性食品 / 脂質代謝 |
Outline of Final Research Achievements |
We investigated the effect of docosenoic acid and icosenoic acid, the abundant monounsaturated fatty acids in the saury oil, on the type-2 diabetic mellitus and atopic dermatitis. Supplementation with docosenoic acid and icosenoic acid had reduced Atopic dermatitis like skin lesions and the frequency of scratching episodes in a time-dependent manner on atopic NC/Nga mice. Furthermore, docosenoic acid and icosenoic acid had reduced weight and insulin sensitivity had improved on the type-2 diabetic KK-Ay mice. From these results, it appears that docosenoic acid and icosenoic acid can contribute to the prevention of a lifestyle-related disease and the allergic disease.
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Report
(5 results)
Research Products
(38 results)
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[Presentation] 魚油とサメ肝油の栄養機能2014
Author(s)
西川 正純
Organizer
日本脂質栄養学会第23回大会
Place of Presentation
東京国際交流館
Year and Date
2014-08-29 – 2014-08-30
Related Report
Invited
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