Development of egg-hatching assays for evaluatingTCBZ resistance of parthenogenic Fasciola sp.
| Project/Area Number |
24580420
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Iwate University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | parthenogenic Fasciola / hybridyzation / Fasciola hepatica / diploid / 単為生殖型肝蛭 / トリクラベンダゾール / 虫卵孵化 |
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| Outline of Final Research Achievements |
Experimental production of TCBZ-resistant parthenogenic Fasciola sp. was attempted due to hybridyzation between Fasciola hepatica and diploid parthenogenic Fasciola sp.(Fg lineage). Hybrid F1 and F2 descendants produced had aberrant meiotic division in their spermatogenesis as well as wild-type parthenogenic Fasciola sp. However, the descendants were proved to be TCBZ-susceptible due to TCBZ administration experiments, and the development of egg-hatching assay turn out not to be ture.
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Report
(4 results)
Research Products
(45 results)
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[Journal Article] Morphological and molecular characterization of Explanatum explanatum from cattle and buffaloes in Myanmar.2013
Author(s)
Ichikawa, M., Kondoh, D., Bawn, S., Maw, N. N., Htun, L. L., Thein, M., Gyi, A., Sunn, K., Katakura, K. and Itagaki, T.
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Journal Title
J. Vet. Med. Sci.
Volume: 75
Pages: 309-314
Related Report
Peer Reviewed
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[Journal Article] Vaccine potential of recombinant cathepsin B against Fasciola gigantica.2013
Author(s)
Pathanin Chantree, Manussabhorn Phatsara, Krai Meemon, Pannigan Chaichanasak,Narin Changklungmoa, Pornanan Kueakhai, Natcha Lorsuwannarat, Kant Sangpairoj, Sineenart Songkoomkrong, Chaitip Wanichanon, Tadashi Itagaki, Prasert Sobhon
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Journal Title
Experimental Parasitology
Volume: 135
Pages: 102-109
Related Report
Peer Reviewed
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[Journal Article] Molecular identification of Fasciola spp. (Digenea: Platyhelminthes) in cattle from Vietnam.2012
Author(s)
Nguyen, S., Amer, S., Ichikawa, M., Itagaki, T., Fukuda, Y. and Nakai, Y.
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Journal Title
Parasite
Volume: 19
Pages: 85-89
Related Report
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