| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Outline of Final Research Achievements |
Asymmetric synthesis of (－)-trans-blechnic acid, a dihydrobenzofuran neolignan natural product, has been achieved by employing Rh(II)-catalyzed intramolecular C-H insertion reaction of aryldiazoacetate and Pd(II)-catalyzed intermolecular C-H olefination reaction as key steps.
Asymmetric synthesis of (－)-E-δ-viniferin, a trans-resveratrol dimer natural product containing a dihydrobenzofuran ring, has been achieved by exploiting Rh(II)-catalyzed intramolecular C-H insertion reaction of a diaryldiazomethane derivative as a key step.
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