| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
Cross-reactivity is the reaction against a different but similar antigen. We hypotheses that the recognition site of antibody is equivalent to the receptor domain, and utilizing the cross-reactivity, it makes possible to discover the new structures which possess the equivalent of pharmacophar as a small molecule antigen. We developed the new approach for natural product drug discovery utilizing the cross-reactivity of anti-morphine monoclonal antibody (MAb).
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