| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
During embryogenesis, axons reach their specific targets correctly to form the complex neural network found in the mature functional nervous system. Several groups of axon guidance molecules such as semaphorins, ephrins, netrins, and Slits have been reported to repel or attract growing axons that express their cognate receptors. Herein, I report the cloning and characterization of novel semaphorin genes. These semaphorin genes might repel axons of the specific types during development.
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