| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Outline of Final Research Achievements |
I have developed a flat-plate electrocardiogram/piezoelectric-element hybrid sensor for continuous electrocardiographic recording in freely-moving mice without the need for electrode-implantation surgery and made a patent application on the hybrid-sensor system (#2015-058838). As the sensor required the sweating (emotional sweating) on the soles of mice for the electrocardiographic recording, experiments were performed during under stress and during sleep, and there were several findings as follows: (1) Mice exhibit heartrate elevation with sweating on their soles as psychological-stress response when exposed to sounds or vibration and when being gazed at by an experimenter. (2) In contrast to humans, mice exhibit sweating on their soles during sleep. (3) The response of (1) becomes a more dynamic change in heart rate when conducted during sleep, and furthermore, mice exhibit an arrhythmia thought to be the atrial fibrillation.
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