| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Outline of Final Research Achievements |
In the hippacampus, it was reported that the cell division occurs during specific time-window in a day. However, its mechanism remains to be fully clarified. In this study, we tried to clarify how the molecular clock regulates the circadian proliferation of the neural stem cells. We found that Sirt1 is causally involved in the circaidan proliferation of the neural stem cells using automatic real-time monitoring system for cell division.
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