| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
About 70% of neurons in the mesopontine tegmentum displayed higher activity during paradoxical sleep (PS), and half of them started to increase their firing prior to the onset of PS. Most of them showed phasic activity in some periods during PS, about 40% of them discharged in synchronous with rapid eye movement. Neurons in the mesopontine tegmentum have a role in initiating PS, and in regulating phasic phenomena during PS. Neurobiotin labeling of the neurons in VGAD-vinus transgenic rats revealed that GABAergic neurons generate action potentials with shorter duration and higher firing rate. Multi units recording through multi-point electrode revealed that several serotonergic neurons in the dorsal raphe discharged synchronously, resulting in constant and tonic firing in the serotonergic neurons.
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