| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Vestibulo-cardiovascular reflex (V-C reflex) has a significant role in controlling arterial pressure upon standing. However, the vestibular system is known to be highly plastic, thus it is possible that sensitivity of V-C reflex is suppressed if subjects are under a different gravitational environment, microgravity. This might be a responsible mechanism for post-flight orthostatic hypotension. To examine this, sensitivity of V-C reflex was examined before and after 4 to 6 months stay in the International Space Station. V-C reflex was impaired 1 day to 2 weeks after landing, and arterial pressure dropped upon standing. The impaired vestibular function can be ameliorated by subsensory weak galvanic vestibular stimulation.
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