| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Outline of Final Research Achievements |
Myocardial bridge (MB) is an anatomical variant covering a part of the coronary artery. The existence of MB contributes a progression of atherosclerosis in the segment proximal to an MB, and this atherosclerotic evolution in cases with myocardial infarction was aggregated at 2.0 cm from the MB entrance. In this study, using perfused autopsy hearts, the association of the existence of MB with arterial stenosis proximal to an MB was investigated by statistical analyses. The arterial segment proximal to an MB demonstrated larger stenosis than that in the MB segment, and the largest stenosis was aggregated at 2.5 cm proximal to the MB entrance.
In non-infarcted heart, the presence of MB may enhance the atherosclerosis evolution at the decisive site (2.5 cm) proximal to MB entrance. It's considered that the presence of MB in the running course of the LAD contributes a strong stenosis in the LAD segment proximal to MB entrance, leading further to myocardial infarction.
|
