| Project/Area Number |
24590639
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical sociology
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| Research Institution | Nippon Medical School |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SAITO Ayumu 東京大学, 医科学研究所, 技術職員 (00526759)
NAGASAKI Masao 東北大学, 東北メディカル・メガバンク構, 教授 (90396862)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 糖尿病 / 血糖値 / シミュレーションモデル |
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| Outline of Final Research Achievements |
Prevalence of diabetes mellitus (DM), especially type 2 DM (T2DM) has been increasing by the lifestyle westernization. Recent studies suggested that the lifestyle intervention in diet and physical exercise could prevent the development of T2DM. Thus, the lifestyle modification and understanding of consciousness of disease are important for diabetic and prediabetic patients. However, prolonged treatment of a patient with DM often cause the defect of medication regimen compliance and lifestyle improvement, and eventually increase the risk of complications. In this study, we developed a computer simulation model of glycemic control implementing the interaction among three organs (small intestine, liver, and pancreas) which play pivotal roles in glycemic control, using Cell Illustrator (CI) as the computer simulation software. This may be useful for the communication between DM educators and patients, and support the improvement of medication regimen compliance and lifestyle of patients.
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