| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
V02 strain: the spreading multi drug-resistant Mycobacterium tuberculosis stain in Osaka Prefecture, were subjected to genome-wide analysis by next-generation sequencing. Compared with H37Rv, 1,445 SNPs were common to all 15 isolates belonging to V02 strain. Although 51 SNPs were found among 15 isolates of V02 strain, and V02 strains were divided into two groups by two SNPs (A to C at 7582 and G to A at 3157508). These results shows the existence of V02 strains was not from one outbreak causing by one infectious source but the isolates of V02 may have common ancestor.
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